Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan
While knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded. The properties of these venoms are now being studied with the aim to design and develop new therapeutic drugs. Far from evaluating t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-04-01
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| Series: | Toxins |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-6651/7/4/1126 |
| _version_ | 1798043089273618432 |
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| author | Miguel Moreno Ernest Giralt |
| author_facet | Miguel Moreno Ernest Giralt |
| author_sort | Miguel Moreno |
| collection | DOAJ |
| description | While knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded. The properties of these venoms are now being studied with the aim to design and develop new therapeutic drugs. Far from evaluating the extensive number of monographs, journals and books related to bee and wasp venoms and the therapeutic effect of these toxins in numerous diseases, the following review focuses on the three most characterized peptides, namely melittin, apamin, and mastoparan. Here, we update information related to these compounds from the perspective of applied science and discuss their potential therapeutic and biotechnological applications in biomedicine. |
| first_indexed | 2024-04-11T22:44:44Z |
| format | Article |
| id | doaj.art-dff3ec3c4b704735985b8b752340e570 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-11T22:44:44Z |
| publishDate | 2015-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-dff3ec3c4b704735985b8b752340e5702022-12-22T03:58:48ZengMDPI AGToxins2072-66512015-04-01741126115010.3390/toxins7041126toxins7041126Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and MastoparanMiguel Moreno0Ernest Giralt1Chemistry and Molecular Pharmacology, Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, Barcelona 08028, SpainChemistry and Molecular Pharmacology, Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, Barcelona 08028, SpainWhile knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded. The properties of these venoms are now being studied with the aim to design and develop new therapeutic drugs. Far from evaluating the extensive number of monographs, journals and books related to bee and wasp venoms and the therapeutic effect of these toxins in numerous diseases, the following review focuses on the three most characterized peptides, namely melittin, apamin, and mastoparan. Here, we update information related to these compounds from the perspective of applied science and discuss their potential therapeutic and biotechnological applications in biomedicine.http://www.mdpi.com/2072-6651/7/4/1126beewaspvenommelittinapaminmastoparan |
| spellingShingle | Miguel Moreno Ernest Giralt Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan Toxins bee wasp venom melittin apamin mastoparan |
| title | Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan |
| title_full | Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan |
| title_fullStr | Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan |
| title_full_unstemmed | Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan |
| title_short | Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan |
| title_sort | three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use melittin apamin and mastoparan |
| topic | bee wasp venom melittin apamin mastoparan |
| url | http://www.mdpi.com/2072-6651/7/4/1126 |
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