Effect of nitazoxanide and spiramycin metronidazole combination in acute experimental toxoplasmosis

Effect of nitazoxanide and spiramycin metronidazole combination in acute experimental toxoplasmosis

Successful treatment of Toxoplasma gondii infection is difficult to attain. This study was designed to evaluate the efficacy of sulfamethoxazole-trimethoprim (SMZ-TMP), as the reference drug, nitazoxanide (NTZ), spiramycin (SP) and SP-metronidazole against the virulent RH T. gondii strain in acute e...

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Bibliographic Details
Main Authors: Amal FarahatAllam, Amel Youssef Shehab, Nerrmine Mogahed Fawzy Hussein Mogahed, Hoda Fahmy Farag, Yasmen Elsayed, Naglaa Fathi Abd El-Latif
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Heliyon
Subjects:
Toxicology
Toxoplasma gondii
Nitazoxanide
Spiramycin
Sulfamethoxazole-trimethoprim
Spiramycin-metronidazole
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020305065

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