Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri
In the ascidian Botryllus schlosseri, we studied the effects of hemocyte incubation with foreigncells, such as bacteria, bacterial spores and yeast. In the presence of yeast and bacterial spores,morula cells, a common cell type in botryllid ascidians, changed their morphology, releasephenoloxidase i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Modena and Reggio Emilia
2005-01-01
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| Series: | Invertebrate Survival Journal |
| Subjects: | |
| Online Access: | http://www.isj.unimo.it/articoli/ISJ009.pdf |
| _version_ | 1819024072154021888 |
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| author | L Ballarin A Menin N Franchi G Bertoloni F Cima |
| author_facet | L Ballarin A Menin N Franchi G Bertoloni F Cima |
| author_sort | L Ballarin |
| collection | DOAJ |
| description | In the ascidian Botryllus schlosseri, we studied the effects of hemocyte incubation with foreigncells, such as bacteria, bacterial spores and yeast. In the presence of yeast and bacterial spores,morula cells, a common cell type in botryllid ascidians, changed their morphology, releasephenoloxidase in the medium, thus causing an increase in cytotoxicity, and express moleculesrecognised by anti-IL-1-a- and anti-TNF-a-antibodies. These effects were not observed whenhemocytes were incubated with both gram-positive (Staphylococcus aureus) and gram-negative(Escherichia coli) bacteria. Considering that morula cells are the main source of molecules recognisedby anti-cytokine-antibodies we suggest an immunosurveillance role of these cells, which may influenceimmune responses such as phagocytosis. |
| first_indexed | 2024-12-21T04:48:58Z |
| format | Article |
| id | doaj.art-dff6b4beb0364ead86aa0c50b79bbffc |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-21T04:48:58Z |
| publishDate | 2005-01-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-dff6b4beb0364ead86aa0c50b79bbffc2022-12-21T19:15:31ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2005-01-012115Morula cells and non-self recognition in the compound ascidian Botryllus schlosseriL BallarinA MeninN FranchiG BertoloniF CimaIn the ascidian Botryllus schlosseri, we studied the effects of hemocyte incubation with foreigncells, such as bacteria, bacterial spores and yeast. In the presence of yeast and bacterial spores,morula cells, a common cell type in botryllid ascidians, changed their morphology, releasephenoloxidase in the medium, thus causing an increase in cytotoxicity, and express moleculesrecognised by anti-IL-1-a- and anti-TNF-a-antibodies. These effects were not observed whenhemocytes were incubated with both gram-positive (Staphylococcus aureus) and gram-negative(Escherichia coli) bacteria. Considering that morula cells are the main source of molecules recognisedby anti-cytokine-antibodies we suggest an immunosurveillance role of these cells, which may influenceimmune responses such as phagocytosis.http://www.isj.unimo.it/articoli/ISJ009.pdfascidiansBotrylluscytotoxicitymorula cellsphenoloxidaseimmunomodulation |
| spellingShingle | L Ballarin A Menin N Franchi G Bertoloni F Cima Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri Invertebrate Survival Journal ascidians Botryllus cytotoxicity morula cells phenoloxidase immunomodulation |
| title | Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri |
| title_full | Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri |
| title_fullStr | Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri |
| title_full_unstemmed | Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri |
| title_short | Morula cells and non-self recognition in the compound ascidian Botryllus schlosseri |
| title_sort | morula cells and non self recognition in the compound ascidian botryllus schlosseri |
| topic | ascidians Botryllus cytotoxicity morula cells phenoloxidase immunomodulation |
| url | http://www.isj.unimo.it/articoli/ISJ009.pdf |
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