Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke
Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it. This study aimed to investigate the diagnostic value of serum yclophilin A levels in our study group who presented t...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2017-06-01
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| Series: | Eurasian Journal of Emergency Medicine |
| Subjects: | |
| Online Access: |
http://akademikaciltip.com/archives/archive-detail/article-preview/diagnostic-value-of-cyclophilin-a-in-acute-schemic/21769
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| _version_ | 1797906483730448384 |
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| author | Yunus Karaca Özgür Tatlı Umut Eryiğit Nurhak Aksüt Aynur Şahin Ahmet Menteşe Diler Us Altay Necla Beşlioğlu Mevlüt Karataş Asım Örem |
| author_facet | Yunus Karaca Özgür Tatlı Umut Eryiğit Nurhak Aksüt Aynur Şahin Ahmet Menteşe Diler Us Altay Necla Beşlioğlu Mevlüt Karataş Asım Örem |
| author_sort | Yunus Karaca |
| collection | DOAJ |
| description | Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it. This study aimed to investigate the diagnostic value of serum yclophilin A levels in our study group who presented to the emergency department with symptoms of acute ischemic stroke.Materials and Methods: In total, 114 patients diagnosed with acute ischemic stroke between October 2013 and October 2014 and a control group of 66 healthy volunteers were included. Cyclophilin A levels in the patient and control groups were compared.Results: The median cyclophilin A levels in the patient and control groups measured at the time of presentation were 13.47 (11.97–17.92) ng/mL and 11.54 (8.48–16.22) ng/mL, respectively. These levels were significantly higher in the patient group than in the control group (p<0.05).Conclusion:Plasma cyclophilin A levels were significantly higher in the patient group than in the control group. |
| first_indexed | 2024-04-10T10:22:43Z |
| format | Article |
| id | doaj.art-dff8a42e803143538468047a5a9e976d |
| institution | Directory Open Access Journal |
| issn | 2149-5807 2149-6048 |
| language | English |
| last_indexed | 2024-04-10T10:22:43Z |
| publishDate | 2017-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Eurasian Journal of Emergency Medicine |
| spelling | doaj.art-dff8a42e803143538468047a5a9e976d2023-02-15T16:21:34ZengGalenos YayineviEurasian Journal of Emergency Medicine2149-58072149-60482017-06-01162545610.5152/eajem.2017.3511913049054Diagnostic Value of Cyclophilin A in Acute Ischemic StrokeYunus Karaca0Özgür Tatlı1Umut Eryiğit2Nurhak Aksüt3Aynur Şahin4Ahmet Menteşe5Diler Us Altay6Necla Beşlioğlu7Mevlüt Karataş8Asım Örem9 Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey Clinic of Emergency Medicine, Manisa State Hospital, Manisa, Turkey Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey Department of Biochemistry, Karadeniz Technical University School of Medicine, Trabzon, Turkey Department of Chemical and Chemical Processing Technology, Ordu University School of Ulubey Vocational, Ordu, Turkey Clinic of Emergency Medicine, Gümüşhane State Hospital, Gümüşhane, Turkey Department of Chest Diseases, Recep Tayyip Erdoğan University School of Medicine, Rize, Turkey Department of Biochemistry, Karadeniz Technical University School of Medicine, Trabzon, Turkey Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it. This study aimed to investigate the diagnostic value of serum yclophilin A levels in our study group who presented to the emergency department with symptoms of acute ischemic stroke.Materials and Methods: In total, 114 patients diagnosed with acute ischemic stroke between October 2013 and October 2014 and a control group of 66 healthy volunteers were included. Cyclophilin A levels in the patient and control groups were compared.Results: The median cyclophilin A levels in the patient and control groups measured at the time of presentation were 13.47 (11.97–17.92) ng/mL and 11.54 (8.48–16.22) ng/mL, respectively. These levels were significantly higher in the patient group than in the control group (p<0.05).Conclusion:Plasma cyclophilin A levels were significantly higher in the patient group than in the control group. http://akademikaciltip.com/archives/archive-detail/article-preview/diagnostic-value-of-cyclophilin-a-in-acute-schemic/21769 Acute ischemic strokecyclophilin Aemergency department |
| spellingShingle | Yunus Karaca Özgür Tatlı Umut Eryiğit Nurhak Aksüt Aynur Şahin Ahmet Menteşe Diler Us Altay Necla Beşlioğlu Mevlüt Karataş Asım Örem Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke Eurasian Journal of Emergency Medicine Acute ischemic stroke cyclophilin A emergency department |
| title | Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke |
| title_full | Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke |
| title_fullStr | Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke |
| title_full_unstemmed | Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke |
| title_short | Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke |
| title_sort | diagnostic value of cyclophilin a in acute ischemic stroke |
| topic | Acute ischemic stroke cyclophilin A emergency department |
| url |
http://akademikaciltip.com/archives/archive-detail/article-preview/diagnostic-value-of-cyclophilin-a-in-acute-schemic/21769
|
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