Application of Exogenous GnRH in Food Animal Production

Over several decades, exogenous GnRH and agonists have been employed for controlling reproductive cascades in animals, and treating some reproductive morbidities. The administration of GnRH is used in animals to counter ovarian dysfunction, induce ovulation, and to increase conception and pregnancy...

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Main Authors: A. H. M. Musleh Uddin, Kiro R. Petrovski, Yunmei Song, Sanjay Garg, Roy N. Kirkwood
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/13/12/1891
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author A. H. M. Musleh Uddin
Kiro R. Petrovski
Yunmei Song
Sanjay Garg
Roy N. Kirkwood
author_facet A. H. M. Musleh Uddin
Kiro R. Petrovski
Yunmei Song
Sanjay Garg
Roy N. Kirkwood
author_sort A. H. M. Musleh Uddin
collection DOAJ
description Over several decades, exogenous GnRH and agonists have been employed for controlling reproductive cascades in animals, and treating some reproductive morbidities. The administration of GnRH is used in animals to counter ovarian dysfunction, induce ovulation, and to increase conception and pregnancy rates. GnRH and its agonists are used in the treatment of cystic ovarian degeneration and repeat breeder syndrome. The development of protocols for GnRH administration by intramuscular injection, intramuscular or subcutaneous implants, and intravaginal deposition has empowered their clinical use worldwide. Currently, exogenous GnRH products are a central part of several pre- and post-breeding programs for the enhancement of fertility, including the control of estrous cycles and timing of ovulation, development of fixed-time artificial insemination protocols, improved embryo survival, and the treatment of reproductive morbidity. The aim of the present review is to summarize the application of exogenous GnRH agonists in food animal production.
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spelling doaj.art-dff976a79ef94736b5969af568da76b02023-11-18T08:57:41ZengMDPI AGAnimals2076-26152023-06-011312189110.3390/ani13121891Application of Exogenous GnRH in Food Animal ProductionA. H. M. Musleh Uddin0Kiro R. Petrovski1Yunmei Song2Sanjay Garg3Roy N. Kirkwood4School of Animal & Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, AustraliaDavies Livestock Research Centre, School of Animal & Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, AustraliaClinical and Health Sciences, University of South Australia, Adelaide, SA 5000, AustraliaClinical and Health Sciences, University of South Australia, Adelaide, SA 5000, AustraliaSchool of Animal & Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, SA 5371, AustraliaOver several decades, exogenous GnRH and agonists have been employed for controlling reproductive cascades in animals, and treating some reproductive morbidities. The administration of GnRH is used in animals to counter ovarian dysfunction, induce ovulation, and to increase conception and pregnancy rates. GnRH and its agonists are used in the treatment of cystic ovarian degeneration and repeat breeder syndrome. The development of protocols for GnRH administration by intramuscular injection, intramuscular or subcutaneous implants, and intravaginal deposition has empowered their clinical use worldwide. Currently, exogenous GnRH products are a central part of several pre- and post-breeding programs for the enhancement of fertility, including the control of estrous cycles and timing of ovulation, development of fixed-time artificial insemination protocols, improved embryo survival, and the treatment of reproductive morbidity. The aim of the present review is to summarize the application of exogenous GnRH agonists in food animal production.https://www.mdpi.com/2076-2615/13/12/1891GnRH agonistsartificial inseminationreproductionfood animals
spellingShingle A. H. M. Musleh Uddin
Kiro R. Petrovski
Yunmei Song
Sanjay Garg
Roy N. Kirkwood
Application of Exogenous GnRH in Food Animal Production
Animals
GnRH agonists
artificial insemination
reproduction
food animals
title Application of Exogenous GnRH in Food Animal Production
title_full Application of Exogenous GnRH in Food Animal Production
title_fullStr Application of Exogenous GnRH in Food Animal Production
title_full_unstemmed Application of Exogenous GnRH in Food Animal Production
title_short Application of Exogenous GnRH in Food Animal Production
title_sort application of exogenous gnrh in food animal production
topic GnRH agonists
artificial insemination
reproduction
food animals
url https://www.mdpi.com/2076-2615/13/12/1891
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AT yunmeisong applicationofexogenousgnrhinfoodanimalproduction
AT sanjaygarg applicationofexogenousgnrhinfoodanimalproduction
AT roynkirkwood applicationofexogenousgnrhinfoodanimalproduction