Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

Early life stress (ELS) is a known antecedent for the development of mood disorders such as depression. Orexin neurons drive arousal and motivated behaviors in response to stress. We tested the hypothesis that ELS alters orexin system function and leads to an altered stress-induced behavioral phen...

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Bibliographic Details
Main Authors: Morgan H James, Erin Jane Campbell, Frederick Rohan Walker, Douglas W Smith, Heather N Richardson, Deborah M Hodgson, Christopher V Dayas
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Exercise
Hypothalamus
gender differences
plasticity
stress
maternal separation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00244/full

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