Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts
The current study was carried out to explore the phytochemical, antioxidant potential and antibacterial activities of the crude methanolic extract of A. santolinifolia Turcz. Ex Besser. The antioxidant activity was carried out by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis-3-ethyl...
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| Language: | English |
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Universidade Federal de Uberlândia
2021-10-01
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| Series: | Bioscience Journal |
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| Online Access: | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/54206 |
| _version_ | 1819002857623388160 |
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| author | Tabinda Nowsheen Ali Hazrat Sayed Wadood Ali Shah Shabana Bibi Afshan Begum Muhammad Mukhtiar Adam Khan |
| author_facet | Tabinda Nowsheen Ali Hazrat Sayed Wadood Ali Shah Shabana Bibi Afshan Begum Muhammad Mukhtiar Adam Khan |
| author_sort | Tabinda Nowsheen |
| collection | DOAJ |
| description |
The current study was carried out to explore the phytochemical, antioxidant potential and antibacterial activities of the crude methanolic extract of A. santolinifolia Turcz. Ex Besser. The antioxidant activity was carried out by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) assay, while methanolic extract displayed the highest scavenging activity (DPPH) was 61.31µg/ml on Artemisia santolinifolia root and the lowest (51.05µg/ml) was record for their leaves. Similarly, in (ABTS) the highest activity (89.16µg/ml) was recorded for roots of A. santolinifolia followed by leaves (68.14µg/ml). In low inhibitory concentration assay, the crude methanolic extracts showed significant inhibition against all tested microbes on different concentrations like 25 µg/ml, 50 µg/ml, and 100 µg/ml. The leaves extract of A. santolinifolia AsL showed MIC of 12.5µg/ml for B. subtilis, a gram-positive bacterium, 50µg/ml for gram positive bacteria S. aureus and 37.5 µg/ml for gram negative bacteria P. aeruginosa that is almost equal to the response of standard ciprofloxacin. Our current study revealed that Artemisia santolinifolia root (AsR) exhibited a significant antioxidant potential while AsL showed good antibacterial effect which is suggested to be used for treatment and management of different infectious diseases.
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| first_indexed | 2024-12-20T23:11:46Z |
| format | Article |
| id | doaj.art-dfffa658b81843e5873d8dc3db435a9c |
| institution | Directory Open Access Journal |
| issn | 1981-3163 |
| language | English |
| last_indexed | 2024-12-20T23:11:46Z |
| publishDate | 2021-10-01 |
| publisher | Universidade Federal de Uberlândia |
| record_format | Article |
| series | Bioscience Journal |
| spelling | doaj.art-dfffa658b81843e5873d8dc3db435a9c2022-12-21T19:23:43ZengUniversidade Federal de UberlândiaBioscience Journal1981-31632021-10-0137Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various partsTabinda Nowsheen0Ali Hazrat1Sayed Wadood Ali Shah2Shabana Bibi3Afshan Begum4Muhammad Mukhtiar5Adam Khan6University of MalakandUniversity of MalakandUniversity of MalakandUniversity of MalakandUniversity of PeshawarUniversity of Poonch RawalakotUniversity of Lakki Marwat The current study was carried out to explore the phytochemical, antioxidant potential and antibacterial activities of the crude methanolic extract of A. santolinifolia Turcz. Ex Besser. The antioxidant activity was carried out by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) assay, while methanolic extract displayed the highest scavenging activity (DPPH) was 61.31µg/ml on Artemisia santolinifolia root and the lowest (51.05µg/ml) was record for their leaves. Similarly, in (ABTS) the highest activity (89.16µg/ml) was recorded for roots of A. santolinifolia followed by leaves (68.14µg/ml). In low inhibitory concentration assay, the crude methanolic extracts showed significant inhibition against all tested microbes on different concentrations like 25 µg/ml, 50 µg/ml, and 100 µg/ml. The leaves extract of A. santolinifolia AsL showed MIC of 12.5µg/ml for B. subtilis, a gram-positive bacterium, 50µg/ml for gram positive bacteria S. aureus and 37.5 µg/ml for gram negative bacteria P. aeruginosa that is almost equal to the response of standard ciprofloxacin. Our current study revealed that Artemisia santolinifolia root (AsR) exhibited a significant antioxidant potential while AsL showed good antibacterial effect which is suggested to be used for treatment and management of different infectious diseases. https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/54206Artemisia santolinifoliaAntioxidant PotentialAntibacterial ActivityPhytochemicals. |
| spellingShingle | Tabinda Nowsheen Ali Hazrat Sayed Wadood Ali Shah Shabana Bibi Afshan Begum Muhammad Mukhtiar Adam Khan Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts Bioscience Journal Artemisia santolinifolia Antioxidant Potential Antibacterial Activity Phytochemicals. |
| title | Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts |
| title_full | Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts |
| title_fullStr | Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts |
| title_full_unstemmed | Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts |
| title_short | Phytochemical, antibacterial and antioxidant screening of Artemisia santolinifolia various parts |
| title_sort | phytochemical antibacterial and antioxidant screening of artemisia santolinifolia various parts |
| topic | Artemisia santolinifolia Antioxidant Potential Antibacterial Activity Phytochemicals. |
| url | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/54206 |
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