The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study
No previous study has evaluated the effects of RF on inflammatory and hematological indices of COPD patients. The main objective of the present pilot study was to assess the effects of RF on some inflammatory and hematological indices measured in male patients with stable COPD. Fifteen COPD patients...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-11-01
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| Series: | American Journal of Men's Health |
| Online Access: | https://doi.org/10.1177/1557988318794304 |
| _version_ | 1819226512052715520 |
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| author | Hadhemi Rejeb (MD) Mouna Ben Khelifa (MD) Jihene Ben Abdallah (MD) Sawssan Mrad (MD) Mohamed Ben Rejeb (MD) Abdelaziz Hayouni (MD) Mohamed Benzarti (MD) Khelifa Limem (MD) Mondher Kortas (MD) Sonia Rouatbi (MD, PhD) Helmi Ben Saad (MD, PhD) |
| author_facet | Hadhemi Rejeb (MD) Mouna Ben Khelifa (MD) Jihene Ben Abdallah (MD) Sawssan Mrad (MD) Mohamed Ben Rejeb (MD) Abdelaziz Hayouni (MD) Mohamed Benzarti (MD) Khelifa Limem (MD) Mondher Kortas (MD) Sonia Rouatbi (MD, PhD) Helmi Ben Saad (MD, PhD) |
| author_sort | Hadhemi Rejeb (MD) |
| collection | DOAJ |
| description | No previous study has evaluated the effects of RF on inflammatory and hematological indices of COPD patients. The main objective of the present pilot study was to assess the effects of RF on some inflammatory and hematological indices measured in male patients with stable COPD. Fifteen COPD patients (mean ± SD of age: 71 ± 6 years) who fasted during Ramadan 2017 volunteered for the study. Three sessions (Before-Ramadan, End-Ramadan and After-Ramadan) were selected. Spirometry tests and blood samples were consistently performed 2.5–4.5 hr before the interruption of the fasting. Assessment sessions comprised: spirometry, inflammatory [erythrocyte sedimentation rate (ESR); C-reactive protein (CRP)] and hematological [red and white blood cells (RBC, WBC); hemoglobin; hematocrit; mean corpuscular volume; mean corpuscular hemoglobin; platelets] indices. Findings were analyzed by applying Friedman ANOVA. The median (lower–upper quartiles) of ESR (Before-Ramadan: 3 (2–9), End-Ramadan: 7 (0–13), After-Ramadan: 9 (5–15) mm/h) and CRP (Before-Ramadan: 20 (11–38), End-Ramadan: 15 (9–34), After-Ramadan: 20 (12–46) mg/L) were not significantly affected by RF. Among all the hematological indices, RF influenced only hemoglobin (Before-Ramadan: 14.4 ± 2.2, End-Ramadan: 13.4 ± 1.3, After-Ramadan: 12.2 ± 0.9 g/dL), hematocrit (Before-Ramadan: 45 ± 7, End-Ramadan: 40 ± 4, After-Ramadan: 39 ± 4%), RBC (Before-Ramadan: 5.1 ± 1.0, End-Ramadan: 4.6 ± 0.7, After-Ramadan: 4.4 ± 0.5 10 6 /mm 3 ) and WBC (Before-Ramadan: 8,673 ± 1,911, End-Ramadan: 7,840 ± 1,526, After-Ramadan: 9,507 ± 2,190/mm 3 ). Compared to the Before-Ramadan session, the End-Ramadan session values for hemoglobin, hematocrit, RBC and WBC were lower. Compared to the After-Ramadan session, the End-Ramadan session values for hemoglobin and WBC were higher and lower, respectively. In conclusion, RF caused significant reduction in hemoglobin, hematocrit, RBC and WBC. However, it did not induce any significant changes in the CRP and ESR indices. |
| first_indexed | 2024-12-23T10:26:40Z |
| format | Article |
| id | doaj.art-e0023fd189614a27bfa1a1dabad3e0e5 |
| institution | Directory Open Access Journal |
| issn | 1557-9883 1557-9891 |
| language | English |
| last_indexed | 2024-12-23T10:26:40Z |
| publishDate | 2018-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | American Journal of Men's Health |
| spelling | doaj.art-e0023fd189614a27bfa1a1dabad3e0e52022-12-21T17:50:33ZengSAGE PublishingAmerican Journal of Men's Health1557-98831557-98912018-11-011210.1177/1557988318794304The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot StudyHadhemi Rejeb (MD)0Mouna Ben Khelifa (MD)1Jihene Ben Abdallah (MD)2Sawssan Mrad (MD)3Mohamed Ben Rejeb (MD)4Abdelaziz Hayouni (MD)5Mohamed Benzarti (MD)6Khelifa Limem (MD)7Mondher Kortas (MD)8Sonia Rouatbi (MD, PhD)9Helmi Ben Saad (MD, PhD)10Pulmonary Department, Farhat HACHED Hospital, Sousse, TunisiaPulmonary Department, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Biochemistry, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Biochemistry, Farhat HACHED Hospital, Sousse, TunisiaDepartment of Prevention and Care Safety, Sahloul Hospital, Sousse, TunisiaPulmonary Department, Farhat HACHED Hospital, Sousse, TunisiaPulmonary Department, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Biochemistry, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Hematology, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Physiology and Functional Explorations, Farhat HACHED Hospital, Sousse, TunisiaLaboratory of Physiology. Faculty of Medicine of Sousse, University of Sousse. Sousse, TunisiaNo previous study has evaluated the effects of RF on inflammatory and hematological indices of COPD patients. The main objective of the present pilot study was to assess the effects of RF on some inflammatory and hematological indices measured in male patients with stable COPD. Fifteen COPD patients (mean ± SD of age: 71 ± 6 years) who fasted during Ramadan 2017 volunteered for the study. Three sessions (Before-Ramadan, End-Ramadan and After-Ramadan) were selected. Spirometry tests and blood samples were consistently performed 2.5–4.5 hr before the interruption of the fasting. Assessment sessions comprised: spirometry, inflammatory [erythrocyte sedimentation rate (ESR); C-reactive protein (CRP)] and hematological [red and white blood cells (RBC, WBC); hemoglobin; hematocrit; mean corpuscular volume; mean corpuscular hemoglobin; platelets] indices. Findings were analyzed by applying Friedman ANOVA. The median (lower–upper quartiles) of ESR (Before-Ramadan: 3 (2–9), End-Ramadan: 7 (0–13), After-Ramadan: 9 (5–15) mm/h) and CRP (Before-Ramadan: 20 (11–38), End-Ramadan: 15 (9–34), After-Ramadan: 20 (12–46) mg/L) were not significantly affected by RF. Among all the hematological indices, RF influenced only hemoglobin (Before-Ramadan: 14.4 ± 2.2, End-Ramadan: 13.4 ± 1.3, After-Ramadan: 12.2 ± 0.9 g/dL), hematocrit (Before-Ramadan: 45 ± 7, End-Ramadan: 40 ± 4, After-Ramadan: 39 ± 4%), RBC (Before-Ramadan: 5.1 ± 1.0, End-Ramadan: 4.6 ± 0.7, After-Ramadan: 4.4 ± 0.5 10 6 /mm 3 ) and WBC (Before-Ramadan: 8,673 ± 1,911, End-Ramadan: 7,840 ± 1,526, After-Ramadan: 9,507 ± 2,190/mm 3 ). Compared to the Before-Ramadan session, the End-Ramadan session values for hemoglobin, hematocrit, RBC and WBC were lower. Compared to the After-Ramadan session, the End-Ramadan session values for hemoglobin and WBC were higher and lower, respectively. In conclusion, RF caused significant reduction in hemoglobin, hematocrit, RBC and WBC. However, it did not induce any significant changes in the CRP and ESR indices.https://doi.org/10.1177/1557988318794304 |
| spellingShingle | Hadhemi Rejeb (MD) Mouna Ben Khelifa (MD) Jihene Ben Abdallah (MD) Sawssan Mrad (MD) Mohamed Ben Rejeb (MD) Abdelaziz Hayouni (MD) Mohamed Benzarti (MD) Khelifa Limem (MD) Mondher Kortas (MD) Sonia Rouatbi (MD, PhD) Helmi Ben Saad (MD, PhD) The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study American Journal of Men's Health |
| title | The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study |
| title_full | The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study |
| title_fullStr | The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study |
| title_full_unstemmed | The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study |
| title_short | The Effects of Ramadan-Fasting (RF) on Inflammatory and Hematological Indices of Stable Chronic Obstructive Pulmonary Disease (COPD) Male Patients: A Pilot Study |
| title_sort | effects of ramadan fasting rf on inflammatory and hematological indices of stable chronic obstructive pulmonary disease copd male patients a pilot study |
| url | https://doi.org/10.1177/1557988318794304 |
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