Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs

The literature review tells about current views on the clinical and molecular aspects of antibiotic resistance of Helicobacter pylori (H. pylori). Today, the growing number of H. pylori strains resistant to the first-line regimens is considered to be the main reason of treatment failure. In the tot...

Full description

Bibliographic Details
Main Authors: Y. A. Kucheryaviy, D. M. Andreyev, E. V. Barkalova
Format: Article
Language:Russian
Published: Remedium Group LLC 2013-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/1116
_version_ 1797842132628668416
author Y. A. Kucheryaviy
D. M. Andreyev
E. V. Barkalova
author_facet Y. A. Kucheryaviy
D. M. Andreyev
E. V. Barkalova
author_sort Y. A. Kucheryaviy
collection DOAJ
description The literature review tells about current views on the clinical and molecular aspects of antibiotic resistance of Helicobacter pylori (H. pylori). Today, the growing number of H. pylori strains resistant to the first-line regimens is considered to be the main reason of treatment failure. In the total global population, incidence of drug-resistant strains of H. pylori varies greatly across different geographic areas and correlates with the total frequency of antibiotics intake by the corresponding population. Latest global consensus recommendations regulate a differential choice strategy in selecting eradication therapy. The choice should take into account the level of resistance of H. pylori to clarithromycin, as this type of resistance has greatest clinical significance.
first_indexed 2024-04-09T16:42:51Z
format Article
id doaj.art-e005bd5dc49445969933906e6878b557
institution Directory Open Access Journal
issn 2079-701X
2658-5790
language Russian
last_indexed 2024-04-09T16:42:51Z
publishDate 2013-12-01
publisher Remedium Group LLC
record_format Article
series Медицинский совет
spelling doaj.art-e005bd5dc49445969933906e6878b5572023-04-23T06:56:37ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902013-12-01010111510.21518/2079-701X-2013-10-11-151116Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugsY. A. Kucheryaviy0D. M. Andreyev1E. V. Barkalova2Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Russian Ministry of HealthMoscow State University of Medicine and Dentistry named after A.I. Evdokimov, Russian Ministry of HealthMoscow State University of Medicine and Dentistry named after A.I. Evdokimov, Russian Ministry of HealthThe literature review tells about current views on the clinical and molecular aspects of antibiotic resistance of Helicobacter pylori (H. pylori). Today, the growing number of H. pylori strains resistant to the first-line regimens is considered to be the main reason of treatment failure. In the total global population, incidence of drug-resistant strains of H. pylori varies greatly across different geographic areas and correlates with the total frequency of antibiotics intake by the corresponding population. Latest global consensus recommendations regulate a differential choice strategy in selecting eradication therapy. The choice should take into account the level of resistance of H. pylori to clarithromycin, as this type of resistance has greatest clinical significance.https://www.med-sovet.pro/jour/article/view/1116helicobacter pyloriэрадикацияантибиотикорезистентностькларитромицинметронидазоламоксициллинтетрациклинлевофлоксацинрифабутинфуразолидонhelicobacter pylorieradicationmetronidazoleamoxicillintetracyclinelevofloxacinrifabutinfurazolidone
spellingShingle Y. A. Kucheryaviy
D. M. Andreyev
E. V. Barkalova
Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
Медицинский совет
helicobacter pylori
эрадикация
антибиотикорезистентность
кларитромицин
метронидазол
амоксициллин
тетрациклин
левофлоксацин
рифабутин
фуразолидон
helicobacter pylori
eradication
metronidazole
amoxicillin
tetracycline
levofloxacin
rifabutin
furazolidone
title Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
title_full Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
title_fullStr Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
title_full_unstemmed Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
title_short Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
title_sort сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
topic helicobacter pylori
эрадикация
антибиотикорезистентность
кларитромицин
метронидазол
амоксициллин
тетрациклин
левофлоксацин
рифабутин
фуразолидон
helicobacter pylori
eradication
metronidazole
amoxicillin
tetracycline
levofloxacin
rifabutin
furazolidone
url https://www.med-sovet.pro/jour/article/view/1116
work_keys_str_mv AT yakucheryaviy slinicalandmolecularaspectsofhelicobacterpyloriresistancetoantimicrobialdrugs
AT dmandreyev slinicalandmolecularaspectsofhelicobacterpyloriresistancetoantimicrobialdrugs
AT evbarkalova slinicalandmolecularaspectsofhelicobacterpyloriresistancetoantimicrobialdrugs