Acquisition of lipid metabolic capability in hepatocyte-like cells directly induced from mouse fibroblasts

Acquisition of lipid metabolic capability in hepatocyte-like cells directly induced from mouse fibroblasts

Recently, the numbers of patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have increased worldwide. NAFLD and NASH are known as risk factors for liver cirrhosis and hepatocellular carcinoma. Because many factors can promote the progression of NAFLD and...

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Bibliographic Details
Main Authors: Shizuka eMiura, Atsushi eSuzuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Lipid Metabolism
Liver
fibroblast
reprogramming
hepatocyte
iHep cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00043/full

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