Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis
The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the ob...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Photonics |
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| Online Access: | https://www.mdpi.com/2304-6732/9/2/122 |
| _version_ | 1797477145595871232 |
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| author | Inês Soraia Martins Hugo Filipe Silva Valery Victorovich Tuchin Luís Manuel Oliveira |
| author_facet | Inês Soraia Martins Hugo Filipe Silva Valery Victorovich Tuchin Luís Manuel Oliveira |
| author_sort | Inês Soraia Martins |
| collection | DOAJ |
| description | The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption. |
| first_indexed | 2024-03-09T21:13:28Z |
| format | Article |
| id | doaj.art-e0098de126b04d8992f9ce19061abaf2 |
| institution | Directory Open Access Journal |
| issn | 2304-6732 |
| language | English |
| last_indexed | 2024-03-09T21:13:28Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Photonics |
| spelling | doaj.art-e0098de126b04d8992f9ce19061abaf22023-11-23T21:41:51ZengMDPI AGPhotonics2304-67322022-02-019212210.3390/photonics9020122Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content AnalysisInês Soraia Martins0Hugo Filipe Silva1Valery Victorovich Tuchin2Luís Manuel Oliveira3Faculty of Engineering, University of Porto, FEUP, Rua Dr. Roberto Frias, 4200-465 Porto, PortugalFaculty of Engineering, University of Porto, FEUP, Rua Dr. Roberto Frias, 4200-465 Porto, PortugalScience Medical Center, Saratov State University, 83 Astrakhanskaya Str., 410012 Saratov, RussiaCenter of Innovation in Engineering and Industrial Technology, ISEP, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, PortugalThe pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.https://www.mdpi.com/2304-6732/9/2/122pancreas tissueoptical propertiesscattering coefficientabsorption coefficientpigment detection |
| spellingShingle | Inês Soraia Martins Hugo Filipe Silva Valery Victorovich Tuchin Luís Manuel Oliveira Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis Photonics pancreas tissue optical properties scattering coefficient absorption coefficient pigment detection |
| title | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
| title_full | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
| title_fullStr | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
| title_full_unstemmed | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
| title_short | Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis |
| title_sort | fast estimation of the spectral optical properties of rabbit pancreas and pigment content analysis |
| topic | pancreas tissue optical properties scattering coefficient absorption coefficient pigment detection |
| url | https://www.mdpi.com/2304-6732/9/2/122 |
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