Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease?
Background: Dysphagia is a common and critical condition that occurs in Parkinson's disease (PD), and it may appear in early stages. However, few reliable swallowing-related questionnaires are currently available. Therefore, finding efficient questionnaires for surveying dysphagia during the ea...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | Journal of the Formosan Medical Association |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664619300725 |
| _version_ | 1819136244208107520 |
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| author | Chin-Man Wang Ting-Ta Tsai Szu-Heng Wang Yih-Ru Wu |
| author_facet | Chin-Man Wang Ting-Ta Tsai Szu-Heng Wang Yih-Ru Wu |
| author_sort | Chin-Man Wang |
| collection | DOAJ |
| description | Background: Dysphagia is a common and critical condition that occurs in Parkinson's disease (PD), and it may appear in early stages. However, few reliable swallowing-related questionnaires are currently available. Therefore, finding efficient questionnaires for surveying dysphagia during the early stages of PD is necessary. Purpose: This prospective study aimed to identify the correlations between the M.D. Anderson Dysphagia Inventory (MDADI) with dysphagia limit (DL) and the Unified Parkinson Disease Rating Scale (UPDRS) in early-stage PD. Methods: Forty-two patients with early-stage PD were recruited from a medical center. Data were collected for analysis of swallowing-related quality of life using the MDADI, symptom severity using the UPDRS, and DL using a noninvasive swallowing–respiration assessment system. Results: Our results showed that the MDADI, including its composite and subscales, was not correlated with DL. The composite scores of the MDADI were moderately correlated with the total score of the UPDRS (r = −0.504; p < 0.05) as well as with the second and third sections of the UPDRS scores (r = −0.453 to −0.478; p < 0.05). These results indicated that the impaired MDADI score can predict symptom severity (UPDRS), especially in activities of daily life and motor function. Conclusion: The impaired MDADI for early-stage PD was determined, and decreased DL as a presentation of dysphagia could not be reflected by the MDADI. The MDADI may be used as a quick and convenient questionnaire for predicting the severity of early-stage PD, but not for the screening of early or subclinical dysphagia. Keywords: Dysphagia, Parkinson's disease (PD), M.D. Anderson dysphagia inventory (MDADI), Unified Parkinson disease rating scale (UPDRS), Dysphagia limit (DL) |
| first_indexed | 2024-12-22T10:31:54Z |
| format | Article |
| id | doaj.art-e00a71047090468e95e0cd180ef81b39 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-22T10:31:54Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-e00a71047090468e95e0cd180ef81b392022-12-21T18:29:19ZengElsevierJournal of the Formosan Medical Association0929-66462020-01-011191247253Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease?Chin-Man Wang0Ting-Ta Tsai1Szu-Heng Wang2Yih-Ru Wu3Department of Physical Medicine and Rehabilitation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC; Corresponding author. Department of Physical Medicine and Rehabilitation, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. Fax: +886 3 327 4850.Department of Physical Medicine and Rehabilitation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROCDepartment of Physical Medicine and Rehabilitation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROCCollege of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC; Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC; Corresponding author. Department of Neurology, Linkou Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan, ROC. Fax: +886 3 3287226.Background: Dysphagia is a common and critical condition that occurs in Parkinson's disease (PD), and it may appear in early stages. However, few reliable swallowing-related questionnaires are currently available. Therefore, finding efficient questionnaires for surveying dysphagia during the early stages of PD is necessary. Purpose: This prospective study aimed to identify the correlations between the M.D. Anderson Dysphagia Inventory (MDADI) with dysphagia limit (DL) and the Unified Parkinson Disease Rating Scale (UPDRS) in early-stage PD. Methods: Forty-two patients with early-stage PD were recruited from a medical center. Data were collected for analysis of swallowing-related quality of life using the MDADI, symptom severity using the UPDRS, and DL using a noninvasive swallowing–respiration assessment system. Results: Our results showed that the MDADI, including its composite and subscales, was not correlated with DL. The composite scores of the MDADI were moderately correlated with the total score of the UPDRS (r = −0.504; p < 0.05) as well as with the second and third sections of the UPDRS scores (r = −0.453 to −0.478; p < 0.05). These results indicated that the impaired MDADI score can predict symptom severity (UPDRS), especially in activities of daily life and motor function. Conclusion: The impaired MDADI for early-stage PD was determined, and decreased DL as a presentation of dysphagia could not be reflected by the MDADI. The MDADI may be used as a quick and convenient questionnaire for predicting the severity of early-stage PD, but not for the screening of early or subclinical dysphagia. Keywords: Dysphagia, Parkinson's disease (PD), M.D. Anderson dysphagia inventory (MDADI), Unified Parkinson disease rating scale (UPDRS), Dysphagia limit (DL)http://www.sciencedirect.com/science/article/pii/S0929664619300725 |
| spellingShingle | Chin-Man Wang Ting-Ta Tsai Szu-Heng Wang Yih-Ru Wu Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? Journal of the Formosan Medical Association |
| title | Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? |
| title_full | Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? |
| title_fullStr | Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? |
| title_full_unstemmed | Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? |
| title_short | Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease? |
| title_sort | does the m d anderson dysphagia inventory correlate with dysphagia limit and the unified parkinson disease rating scale in early stage parkinson s disease |
| url | http://www.sciencedirect.com/science/article/pii/S0929664619300725 |
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