Liposuction-induced metabolic alterations – the effect on insulin sensitivity, adiponectin, leptin and resistin

Liposuction surgically removes subcutaneous abdominal tissue (SAT) and has almost no effect on visceral abdominal tissue (VAT) depot. However, some authors suggest that deep layers of SAT are functionally similar to VAT and the amount of deep subcutaneous abdominal adipose tissue is strongly related...

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Bibliographic Details
Main Authors: Magdalena Gibas-Dorna, Piotr Turkowski, Małgorzata Bernatek, Kinga Mikrut, Justyna Kupsz, Jacek Piątek
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2015-12-01
Series:Journal of Medical Science
Subjects:
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/7
Description
Summary:Liposuction surgically removes subcutaneous abdominal tissue (SAT) and has almost no effect on visceral abdominal tissue (VAT) depot. However, some authors suggest that deep layers of SAT are functionally similar to VAT and the amount of deep subcutaneous abdominal adipose tissue is strongly related to insulin resistance in a manner nearly identical to that of visceral adiposity. Moreover, SAT determines leptin secretion which indirectly reflects the level of insulin sensitivity in the body. Thus, the immediate removal of SAT could potentially affect metabolic profile of a patient. The current data are conflicting and cannot bring a clear evidence suggesting that liposuction itself results in important metabolic outcomes and, on the other hand, cannot exclude such a possibility. This review summarizes the liposuction-induced metabolic changes with regard to release of major adipokines and insulin sensitivity.
ISSN:2353-9798
2353-9801