European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea

Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP)...

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Main Authors: Winfried Randerath, Johan Verbraecken, Christel A.L. de Raaff, Jan Hedner, Simon Herkenrath, Winfried Hohenhorst, Tina Jakob, Oreste Marrone, Marie Marklund, Walter T. McNicholas, Rebecca L. Morgan, Jean-Louis Pepin, Sofia Schiza, Nicole Skoetz, Dan Smyth, Jörg Steier, Thomy Tonia, Wojciech Trzepizur, Piet-Heijn van Mechelen, Peter Wijkstra
Format: Article
Language:English
Published: European Respiratory Society 2021-12-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/30/162/210200.full
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author Winfried Randerath
Johan Verbraecken
Christel A.L. de Raaff
Jan Hedner
Simon Herkenrath
Winfried Hohenhorst
Tina Jakob
Oreste Marrone
Marie Marklund
Walter T. McNicholas
Rebecca L. Morgan
Jean-Louis Pepin
Sofia Schiza
Nicole Skoetz
Dan Smyth
Jörg Steier
Thomy Tonia
Wojciech Trzepizur
Piet-Heijn van Mechelen
Peter Wijkstra
author_facet Winfried Randerath
Johan Verbraecken
Christel A.L. de Raaff
Jan Hedner
Simon Herkenrath
Winfried Hohenhorst
Tina Jakob
Oreste Marrone
Marie Marklund
Walter T. McNicholas
Rebecca L. Morgan
Jean-Louis Pepin
Sofia Schiza
Nicole Skoetz
Dan Smyth
Jörg Steier
Thomy Tonia
Wojciech Trzepizur
Piet-Heijn van Mechelen
Peter Wijkstra
author_sort Winfried Randerath
collection DOAJ
description Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP) therapies for OSA, we present recommendations determined by a systematic review of the literature. It is an update of the 2011 ERS statement on non-CPAP therapies, advanced into a clinical guideline. A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear–nose–throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. Eight key clinical questions were generated and a systematic review was conducted to identify published randomised clinical trials that answered these questions. We used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to assess the quality of the evidence and the strength of recommendations. The resulting guideline addresses gastric bypass surgery, custom-made dual-block mandibular advancement devices, hypoglossal nerve stimulation, myofunctional therapy, maxillo-mandibular osteotomy, carbonic anhydrase inhibitors and positional therapy. These recommendations can be used to benchmark quality of care for people with OSA across Europe and to improve outcomes.
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spelling doaj.art-e00b7a21c4e040759442341d5a771f6f2022-12-21T17:22:08ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172021-12-013016210.1183/16000617.0200-20210200-2021European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoeaWinfried Randerath0Johan Verbraecken1Christel A.L. de Raaff2Jan Hedner3Simon Herkenrath4Winfried Hohenhorst5Tina Jakob6Oreste Marrone7Marie Marklund8Walter T. McNicholas9Rebecca L. Morgan10Jean-Louis Pepin11Sofia Schiza12Nicole Skoetz13Dan Smyth14Jörg Steier15Thomy Tonia16Wojciech Trzepizur17Piet-Heijn van Mechelen18Peter Wijkstra19 Bethanien Hospital, Clinic of Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute of Pneumology at the University of Cologne, Solingen, Germany Antwerp University Hospital and University of Antwerp, Edegem (Antwerp), Belgium Amsterdam UMC, Dept of Surgery, Amsterdam, The Netherlands Dept of Sleep Medicine, Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden Bethanien Hospital, Clinic of Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute of Pneumology at the University of Cologne, Solingen, Germany Alfried Krupp Hospital, Dept of Otolaryngology, Essen, Germany Evidence-based Oncology, Dept I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany National Research Council of Italy, Institute for Biomedical Research and Innovation, Palermo, Italy Dept of Odontology, Faculty of Medicine, Umeå University, Umeå, Sweden School of Medicine, University College Dublin, Dublin, Ireland Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada EFCR Sleep and Respiration Unit CHU Grenoble, Grenoble, France Sleep Disorders Unit, Dept of Respiratory Medicine, Medical School, University of Crete, Greece Evidence-based Oncology, Dept I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany European Lung Foundation, Sheffield, UK Lane Fox Unit and Sleep Disorders Centre at Guy's & St Thomas’ NHS Foundation Trust, Centre for Human & Applied Physiological Sciences, King's College London, London, UK Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland Dept of Respiratory and Sleep Medicine, Angers University hospital, Angers, France European Lung Foundation, Sheffield, UK Dept of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP) therapies for OSA, we present recommendations determined by a systematic review of the literature. It is an update of the 2011 ERS statement on non-CPAP therapies, advanced into a clinical guideline. A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear–nose–throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. Eight key clinical questions were generated and a systematic review was conducted to identify published randomised clinical trials that answered these questions. We used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to assess the quality of the evidence and the strength of recommendations. The resulting guideline addresses gastric bypass surgery, custom-made dual-block mandibular advancement devices, hypoglossal nerve stimulation, myofunctional therapy, maxillo-mandibular osteotomy, carbonic anhydrase inhibitors and positional therapy. These recommendations can be used to benchmark quality of care for people with OSA across Europe and to improve outcomes.http://err.ersjournals.com/content/30/162/210200.full
spellingShingle Winfried Randerath
Johan Verbraecken
Christel A.L. de Raaff
Jan Hedner
Simon Herkenrath
Winfried Hohenhorst
Tina Jakob
Oreste Marrone
Marie Marklund
Walter T. McNicholas
Rebecca L. Morgan
Jean-Louis Pepin
Sofia Schiza
Nicole Skoetz
Dan Smyth
Jörg Steier
Thomy Tonia
Wojciech Trzepizur
Piet-Heijn van Mechelen
Peter Wijkstra
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
European Respiratory Review
title European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
title_full European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
title_fullStr European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
title_full_unstemmed European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
title_short European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
title_sort european respiratory society guideline on non cpap therapies for obstructive sleep apnoea
url http://err.ersjournals.com/content/30/162/210200.full
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