Neonatal fungal infections: new strategies in diagnosis

In Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standa...

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Main Author: Angelica Dessì
Format: Article
Language:English
Published: Hygeia Press di Corridori Marinella 2014-09-01
Series:Journal of Pediatric and Neonatal Individualized Medicine
Subjects:
Online Access:https://www.jpnim.com/index.php/jpnim/article/view/172
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author Angelica Dessì
author_facet Angelica Dessì
author_sort Angelica Dessì
collection DOAJ
description In Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standard” in the diagnosis of neonatal fungal sepsis is positive blood culture. Since neonatal sepsis is a multiorgan disorder that leads to metabolic changes in the organism, new technologies such as metabolomics are becoming a promising method in early diagnosis and are capable of predicting onsets, thus allowing personalized treatment and monitoring of neonatal sepsis. Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy) · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiou
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spelling doaj.art-e00bcf6ca67f4156a74d23c0bdad01e42022-12-22T03:39:33ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922014-09-0132e030222e03022210.7363/030222138Neonatal fungal infections: new strategies in diagnosisAngelica Dessì0Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, AOU and University of Cagliari, ItalyIn Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standard” in the diagnosis of neonatal fungal sepsis is positive blood culture. Since neonatal sepsis is a multiorgan disorder that leads to metabolic changes in the organism, new technologies such as metabolomics are becoming a promising method in early diagnosis and are capable of predicting onsets, thus allowing personalized treatment and monitoring of neonatal sepsis. Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy) · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiouhttps://www.jpnim.com/index.php/jpnim/article/view/172fungal infectionsnewbornsepsismetabolomics
spellingShingle Angelica Dessì
Neonatal fungal infections: new strategies in diagnosis
Journal of Pediatric and Neonatal Individualized Medicine
fungal infections
newborn
sepsis
metabolomics
title Neonatal fungal infections: new strategies in diagnosis
title_full Neonatal fungal infections: new strategies in diagnosis
title_fullStr Neonatal fungal infections: new strategies in diagnosis
title_full_unstemmed Neonatal fungal infections: new strategies in diagnosis
title_short Neonatal fungal infections: new strategies in diagnosis
title_sort neonatal fungal infections new strategies in diagnosis
topic fungal infections
newborn
sepsis
metabolomics
url https://www.jpnim.com/index.php/jpnim/article/view/172
work_keys_str_mv AT angelicadessi neonatalfungalinfectionsnewstrategiesindiagnosis