Neonatal fungal infections: new strategies in diagnosis
In Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standa...
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Format: | Article |
Language: | English |
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Hygeia Press di Corridori Marinella
2014-09-01
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Series: | Journal of Pediatric and Neonatal Individualized Medicine |
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Online Access: | https://www.jpnim.com/index.php/jpnim/article/view/172 |
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author | Angelica Dessì |
author_facet | Angelica Dessì |
author_sort | Angelica Dessì |
collection | DOAJ |
description | In Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standard” in the diagnosis of neonatal fungal sepsis is positive blood culture. Since neonatal sepsis is a multiorgan disorder that leads to metabolic changes in the organism, new technologies such as metabolomics are becoming a promising method in early diagnosis and are capable of predicting onsets, thus allowing personalized treatment and monitoring of neonatal sepsis.
Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy) · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology
Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiou |
first_indexed | 2024-04-12T08:52:09Z |
format | Article |
id | doaj.art-e00bcf6ca67f4156a74d23c0bdad01e4 |
institution | Directory Open Access Journal |
issn | 2281-0692 |
language | English |
last_indexed | 2024-04-12T08:52:09Z |
publishDate | 2014-09-01 |
publisher | Hygeia Press di Corridori Marinella |
record_format | Article |
series | Journal of Pediatric and Neonatal Individualized Medicine |
spelling | doaj.art-e00bcf6ca67f4156a74d23c0bdad01e42022-12-22T03:39:33ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922014-09-0132e030222e03022210.7363/030222138Neonatal fungal infections: new strategies in diagnosisAngelica Dessì0Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, AOU and University of Cagliari, ItalyIn Neonatal Intensive Care Unit, fungal sepsis are the third leading cause of late onset sepsis among very low birth weight neonates. Many of biomarkers known are neither sensitive nor specific enough to provide an accurate diagnosis of invasive fungal infections. Indeed even today, the “gold standard” in the diagnosis of neonatal fungal sepsis is positive blood culture. Since neonatal sepsis is a multiorgan disorder that leads to metabolic changes in the organism, new technologies such as metabolomics are becoming a promising method in early diagnosis and are capable of predicting onsets, thus allowing personalized treatment and monitoring of neonatal sepsis. Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy) · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiouhttps://www.jpnim.com/index.php/jpnim/article/view/172fungal infectionsnewbornsepsismetabolomics |
spellingShingle | Angelica Dessì Neonatal fungal infections: new strategies in diagnosis Journal of Pediatric and Neonatal Individualized Medicine fungal infections newborn sepsis metabolomics |
title | Neonatal fungal infections: new strategies in diagnosis |
title_full | Neonatal fungal infections: new strategies in diagnosis |
title_fullStr | Neonatal fungal infections: new strategies in diagnosis |
title_full_unstemmed | Neonatal fungal infections: new strategies in diagnosis |
title_short | Neonatal fungal infections: new strategies in diagnosis |
title_sort | neonatal fungal infections new strategies in diagnosis |
topic | fungal infections newborn sepsis metabolomics |
url | https://www.jpnim.com/index.php/jpnim/article/view/172 |
work_keys_str_mv | AT angelicadessi neonatalfungalinfectionsnewstrategiesindiagnosis |