Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

In humans dietary circulating nitrate accumulates rapidly in saliva through active transport in the salivary glands. By this mechanism resulting salivary nitrate concentrations are 10–20 times higher than in plasma. In the oral cavity nitrate is reduced by commensal bacteria to nitrite, which is sub...

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Dades bibliogràfiques
Autors principals:	Marcelo F Montenegro, Michaela L Sundqvist, Carina Nihlén, Michael Hezel, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg
Format:	Article
Idioma:	English
Publicat:	Elsevier 2016-12-01
Col·lecció:	Redox Biology
Matèries:	Nitric oxide Nitrite Nitrate Diet Microbiome Salivary gland
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S221323171630249X

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