Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

In humans dietary circulating nitrate accumulates rapidly in saliva through active transport in the salivary glands. By this mechanism resulting salivary nitrate concentrations are 10–20 times higher than in plasma. In the oral cavity nitrate is reduced by commensal bacteria to nitrite, which is sub...

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Podrobná bibliografie
Hlavní autoři: Marcelo F Montenegro, Michaela L Sundqvist, Carina Nihlén, Michael Hezel, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2016-12-01
Edice:Redox Biology
Témata:
Nitric oxide
Nitrite
Nitrate
Diet
Microbiome
Salivary gland
On-line přístup:http://www.sciencedirect.com/science/article/pii/S221323171630249X

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