Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

In humans dietary circulating nitrate accumulates rapidly in saliva through active transport in the salivary glands. By this mechanism resulting salivary nitrate concentrations are 10–20 times higher than in plasma. In the oral cavity nitrate is reduced by commensal bacteria to nitrite, which is sub...

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Bibliografiske detaljer
Main Authors:	Marcelo F Montenegro, Michaela L Sundqvist, Carina Nihlén, Michael Hezel, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg
Format:	Article
Sprog:	English
Udgivet:	Elsevier 2016-12-01
Serier:	Redox Biology
Fag:	Nitric oxide Nitrite Nitrate Diet Microbiome Salivary gland
Online adgang:	http://www.sciencedirect.com/science/article/pii/S221323171630249X

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