Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

In humans dietary circulating nitrate accumulates rapidly in saliva through active transport in the salivary glands. By this mechanism resulting salivary nitrate concentrations are 10–20 times higher than in plasma. In the oral cavity nitrate is reduced by commensal bacteria to nitrite, which is sub...

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Dettagli Bibliografici
Autori principali:	Marcelo F Montenegro, Michaela L Sundqvist, Carina Nihlén, Michael Hezel, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg
Natura:	Articolo
Lingua:	English
Pubblicazione:	Elsevier 2016-12-01
Serie:	Redox Biology
Soggetti:	Nitric oxide Nitrite Nitrate Diet Microbiome Salivary gland
Accesso online:	http://www.sciencedirect.com/science/article/pii/S221323171630249X

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