Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research

In humans dietary circulating nitrate accumulates rapidly in saliva through active transport in the salivary glands. By this mechanism resulting salivary nitrate concentrations are 10–20 times higher than in plasma. In the oral cavity nitrate is reduced by commensal bacteria to nitrite, which is sub...

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Bibliografiska uppgifter
Huvudupphovsmän: Marcelo F Montenegro, Michaela L Sundqvist, Carina Nihlén, Michael Hezel, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2016-12-01
Serie:Redox Biology
Ämnen:
Nitric oxide
Nitrite
Nitrate
Diet
Microbiome
Salivary gland
Länkar:http://www.sciencedirect.com/science/article/pii/S221323171630249X

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