Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>)
Thromboelastography (TEG) is a viscoelastic technique that allows the examination of both cellular and plasma protein clotting factors. Thromboelastography helps to investigate the underlying coagulopathy and to monitor therapeutic modalities. Although viscoelastic techniques have been used in human...
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MDPI AG
2023-07-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/14/2389 |
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| author | Tiziana Bassan Josep Pastor Beatriz Agulla Oriol Jornet Jaume Martorell |
| author_facet | Tiziana Bassan Josep Pastor Beatriz Agulla Oriol Jornet Jaume Martorell |
| author_sort | Tiziana Bassan |
| collection | DOAJ |
| description | Thromboelastography (TEG) is a viscoelastic technique that allows the examination of both cellular and plasma protein clotting factors. Thromboelastography helps to investigate the underlying coagulopathy and to monitor therapeutic modalities. Although viscoelastic techniques have been used in human and veterinary medicine, reference ranges in pet rabbits are missing. The objective of this study is to establish the reference-range values of TEG parameters in healthy pet rabbits. 24 healthy pet rabbits of different breeds were included: 16 crossbreeds, four Californians, two lops, one lionhead, and one angora. Four rabbits were less than one year old and 20 were older than one year. Twelve rabbits were neutered females, 10 neutered males, and two were intact females. Health status was assessed through a physical examination, a complete blood work, and a coagulation profile. A TEG 5000 Thromboelastograph Hemostasis System was used with kaolin-activated citrated whole blood. All samples were analysed 30 min postextraction. The TEG reference ranges were reaction time (R) 1.4–6.9 min; clot formation time (K) 0.8–2.2 min; α angle 65.8–82.2 degrees; maximal amplitude (MA) 53.7–73.5 mm; measure of clot strength/firmness (G-value) 5796.6–13,885.9 dyn/cm<sup>2</sup>; and percentage of clot lysis in 30 min (LY30%) 0–41.5%. This study provides the reference ranges of TEG in pet rabbits. |
| first_indexed | 2024-03-11T01:22:59Z |
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| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T01:22:59Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-e0108f276998493cb81830f5c5d7a36f2023-11-18T18:01:45ZengMDPI AGAnimals2076-26152023-07-011314238910.3390/ani13142389Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>)Tiziana Bassan0Josep Pastor1Beatriz Agulla2Oriol Jornet3Jaume Martorell4Fundació Hospital Clínic Veterinari, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainFundació Hospital Clínic Veterinari, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainThromboelastography (TEG) is a viscoelastic technique that allows the examination of both cellular and plasma protein clotting factors. Thromboelastography helps to investigate the underlying coagulopathy and to monitor therapeutic modalities. Although viscoelastic techniques have been used in human and veterinary medicine, reference ranges in pet rabbits are missing. The objective of this study is to establish the reference-range values of TEG parameters in healthy pet rabbits. 24 healthy pet rabbits of different breeds were included: 16 crossbreeds, four Californians, two lops, one lionhead, and one angora. Four rabbits were less than one year old and 20 were older than one year. Twelve rabbits were neutered females, 10 neutered males, and two were intact females. Health status was assessed through a physical examination, a complete blood work, and a coagulation profile. A TEG 5000 Thromboelastograph Hemostasis System was used with kaolin-activated citrated whole blood. All samples were analysed 30 min postextraction. The TEG reference ranges were reaction time (R) 1.4–6.9 min; clot formation time (K) 0.8–2.2 min; α angle 65.8–82.2 degrees; maximal amplitude (MA) 53.7–73.5 mm; measure of clot strength/firmness (G-value) 5796.6–13,885.9 dyn/cm<sup>2</sup>; and percentage of clot lysis in 30 min (LY30%) 0–41.5%. This study provides the reference ranges of TEG in pet rabbits.https://www.mdpi.com/2076-2615/13/14/2389haemostatic disorderrabbitreference rangethromboelastographyviscoelastic method |
| spellingShingle | Tiziana Bassan Josep Pastor Beatriz Agulla Oriol Jornet Jaume Martorell Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) Animals haemostatic disorder rabbit reference range thromboelastography viscoelastic method |
| title | Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) |
| title_full | Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) |
| title_fullStr | Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) |
| title_full_unstemmed | Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) |
| title_short | Reference Range of Kaolin-Activated Thromboelastography (TEG) Values in Healthy Pet Rabbits (<i>Oryctolagus cuniculus</i>) |
| title_sort | reference range of kaolin activated thromboelastography teg values in healthy pet rabbits i oryctolagus cuniculus i |
| topic | haemostatic disorder rabbit reference range thromboelastography viscoelastic method |
| url | https://www.mdpi.com/2076-2615/13/14/2389 |
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