A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP)
This work aimed to carry out a preliminary study on the release of bioactive compounds loaded into starch-based hydrogels produced by high-pressure processing (HPP). As a study case, the experiments were carried out on rice starch HPP hydrogels. Rice starch (20% <i>w</i>/<i>w</i...
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| Format: | Article |
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MDPI AG
2023-06-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/9/7/521 |
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| author | Anna D’Aniello Katerina Koshenaj Giovanna Ferrari |
| author_facet | Anna D’Aniello Katerina Koshenaj Giovanna Ferrari |
| author_sort | Anna D’Aniello |
| collection | DOAJ |
| description | This work aimed to carry out a preliminary study on the release of bioactive compounds loaded into starch-based hydrogels produced by high-pressure processing (HPP). As a study case, the experiments were carried out on rice starch HPP hydrogels. Rice starch (20% <i>w</i>/<i>w</i>) and green tea extract (2% <i>w</i>/<i>w</i>), suspended in distilled water, were treated by HPP at processing conditions enabling starch gelatinisation, namely 600 MPa for 15 min at room temperature. Additional experiments were carried out on samples that were further loaded with glycerol (5% <i>w</i>/<i>w</i>). Gel formation was assessed by analysing the gelatinisation extent, structuring level, and swelling power of the samples. At the processing conditions utilised, stable hydrogels were obtained even in the presence of the extract and/or the glycerol in the starch suspension. As expected, the colour of the hydrogels formed was affected by the addition of green tea extract in the starch solution. HPP starch hydrogels were characterised by Fourier transform infrared spectroscopy (FT-IR) to determine the interactions between the different compounds utilised in the formulation. Moreover, the release kinetics of bioactive compounds from HPP rice starch hydrogels was evaluated using a vertical Franz diffusion cells system, simulating a transdermal pattern. The diffusion of bioactive compounds was measured spectrophotometrically and via HPLC analysis. A controlled release of bioactive compounds from the hydrogel structure was detected, suggesting that small molecules, such as polyphenols, positively interacted with the rice starch HPP hydrogel network that allowed a smooth and constant release of these bioactive compounds over time. |
| first_indexed | 2024-03-11T01:04:08Z |
| format | Article |
| id | doaj.art-e0187e7417dd4392800b4b68a4ed1f25 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-11T01:04:08Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-e0187e7417dd4392800b4b68a4ed1f252023-11-18T19:27:18ZengMDPI AGGels2310-28612023-06-019752110.3390/gels9070521A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP)Anna D’Aniello0Katerina Koshenaj1Giovanna Ferrari2ProdAl Scarl, c/o University of Salerno, 84084 Fisciano, ItalyDepartment of Industrial Engineering, University of Salerno, 84084 Fisciano, ItalyProdAl Scarl, c/o University of Salerno, 84084 Fisciano, ItalyThis work aimed to carry out a preliminary study on the release of bioactive compounds loaded into starch-based hydrogels produced by high-pressure processing (HPP). As a study case, the experiments were carried out on rice starch HPP hydrogels. Rice starch (20% <i>w</i>/<i>w</i>) and green tea extract (2% <i>w</i>/<i>w</i>), suspended in distilled water, were treated by HPP at processing conditions enabling starch gelatinisation, namely 600 MPa for 15 min at room temperature. Additional experiments were carried out on samples that were further loaded with glycerol (5% <i>w</i>/<i>w</i>). Gel formation was assessed by analysing the gelatinisation extent, structuring level, and swelling power of the samples. At the processing conditions utilised, stable hydrogels were obtained even in the presence of the extract and/or the glycerol in the starch suspension. As expected, the colour of the hydrogels formed was affected by the addition of green tea extract in the starch solution. HPP starch hydrogels were characterised by Fourier transform infrared spectroscopy (FT-IR) to determine the interactions between the different compounds utilised in the formulation. Moreover, the release kinetics of bioactive compounds from HPP rice starch hydrogels was evaluated using a vertical Franz diffusion cells system, simulating a transdermal pattern. The diffusion of bioactive compounds was measured spectrophotometrically and via HPLC analysis. A controlled release of bioactive compounds from the hydrogel structure was detected, suggesting that small molecules, such as polyphenols, positively interacted with the rice starch HPP hydrogel network that allowed a smooth and constant release of these bioactive compounds over time.https://www.mdpi.com/2310-2861/9/7/521starch-based hydrogelshigh-pressure processinggreen tea extractbioactive compoundstransdermal release |
| spellingShingle | Anna D’Aniello Katerina Koshenaj Giovanna Ferrari A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) Gels starch-based hydrogels high-pressure processing green tea extract bioactive compounds transdermal release |
| title | A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) |
| title_full | A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) |
| title_fullStr | A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) |
| title_full_unstemmed | A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) |
| title_short | A Preliminary Study on the Release of Bioactive Compounds from Rice Starch Hydrogels Produced by High-Pressure Processing (HPP) |
| title_sort | preliminary study on the release of bioactive compounds from rice starch hydrogels produced by high pressure processing hpp |
| topic | starch-based hydrogels high-pressure processing green tea extract bioactive compounds transdermal release |
| url | https://www.mdpi.com/2310-2861/9/7/521 |
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