TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression

TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression

Myeloid-derived suppressor cells (MDSCs) are a class of heterogeneous myeloid cells, which play an important role in immunosuppression. We intended to find an effective method that can produce MDSCs with significantly better efficiency and promote immune tolerance for transplant rejection through ce...

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Bibliographic Details
Main Authors: Peng Cao, Zejia Sun, Feilong Zhang, Jiandong Zhang, Xiang Zheng, Baozhong Yu, Yong Zhao, Wei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
myeloid derived suppressor cells (MDSCs)
TGF-β
ARG-1
transplant
Immune rejection
immune tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.919674/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.919674/full

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