Crystal structure analysis of the polysialic acid specific O-acetyltransferase NeuO.

Crystal structure analysis of the polysialic acid specific O-acetyltransferase NeuO.

The major virulence factor of the neuroinvasive pathogen Escherichia coli K1 is the K1 capsule composed of α2,8-linked polysialic acid (polySia). K1 strains harboring the CUS-3 prophage modify their capsular polysaccharide by phase-variable O-acetylation, a step that is associated with increased vir...

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Bibliographic Details
Main Authors:	Eike C Schulz, Anne K Bergfeld, Ralf Ficner, Martina Mühlenhoff
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3046976?pdf=render

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