The effects of geometric uncertainties on computational modelling of knee biomechanics

The geometry of the articular components of the knee is an important factor in predicting joint mechanics in computational models. There are a number of uncertainties in the definition of the geometry of cartilage and meniscus, and evaluating the effects of these uncertainties is fundamental to unde...

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Main Authors: Qingen Meng, John Fisher, Ruth Wilcox
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170670
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author Qingen Meng
John Fisher
Ruth Wilcox
author_facet Qingen Meng
John Fisher
Ruth Wilcox
author_sort Qingen Meng
collection DOAJ
description The geometry of the articular components of the knee is an important factor in predicting joint mechanics in computational models. There are a number of uncertainties in the definition of the geometry of cartilage and meniscus, and evaluating the effects of these uncertainties is fundamental to understanding the level of reliability of the models. In this study, the sensitivity of knee mechanics to geometric uncertainties was investigated by comparing polynomial-based and image-based knee models and varying the size of meniscus. The results suggested that the geometric uncertainties in cartilage and meniscus resulting from the resolution of MRI and the accuracy of segmentation caused considerable effects on the predicted knee mechanics. Moreover, even if the mathematical geometric descriptors can be very close to the imaged-based articular surfaces, the detailed contact pressure distribution produced by the mathematical geometric descriptors was not the same as that of the image-based model. However, the trends predicted by the models based on mathematical geometric descriptors were similar to those of the imaged-based models.
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spelling doaj.art-e0218d035f304d49887c80027256f16e2022-12-21T18:00:33ZengThe Royal SocietyRoyal Society Open Science2054-57032017-01-014810.1098/rsos.170670170670The effects of geometric uncertainties on computational modelling of knee biomechanicsQingen MengJohn FisherRuth WilcoxThe geometry of the articular components of the knee is an important factor in predicting joint mechanics in computational models. There are a number of uncertainties in the definition of the geometry of cartilage and meniscus, and evaluating the effects of these uncertainties is fundamental to understanding the level of reliability of the models. In this study, the sensitivity of knee mechanics to geometric uncertainties was investigated by comparing polynomial-based and image-based knee models and varying the size of meniscus. The results suggested that the geometric uncertainties in cartilage and meniscus resulting from the resolution of MRI and the accuracy of segmentation caused considerable effects on the predicted knee mechanics. Moreover, even if the mathematical geometric descriptors can be very close to the imaged-based articular surfaces, the detailed contact pressure distribution produced by the mathematical geometric descriptors was not the same as that of the image-based model. However, the trends predicted by the models based on mathematical geometric descriptors were similar to those of the imaged-based models.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170670the kneebiomechanicscartilagemeniscusgeometric uncertaintiescomputational modelling
spellingShingle Qingen Meng
John Fisher
Ruth Wilcox
The effects of geometric uncertainties on computational modelling of knee biomechanics
Royal Society Open Science
the knee
biomechanics
cartilage
meniscus
geometric uncertainties
computational modelling
title The effects of geometric uncertainties on computational modelling of knee biomechanics
title_full The effects of geometric uncertainties on computational modelling of knee biomechanics
title_fullStr The effects of geometric uncertainties on computational modelling of knee biomechanics
title_full_unstemmed The effects of geometric uncertainties on computational modelling of knee biomechanics
title_short The effects of geometric uncertainties on computational modelling of knee biomechanics
title_sort effects of geometric uncertainties on computational modelling of knee biomechanics
topic the knee
biomechanics
cartilage
meniscus
geometric uncertainties
computational modelling
url https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170670
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