Involvement of CD95 and ligand in CD4+ T-cell and CD8+ T-cell depletion and hepatic cytolysis in patients with chronic viral hepatitis B

Involvement of CD95 and ligand in CD4+ T-cell and CD8+ T-cell depletion and hepatic cytolysis in patients with chronic viral hepatitis B

Background: Chronic viral hepatitis B (HBV) is characterised by progressive hepatocyte destruction and T-cell depletion. The mechanisms of the CD95-CD95 ligand (CD95L) signalling pathway during this chronic disease and the cirrhotic process remains unclear. Objective: We evaluated the involvement o...

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Bibliographic Details
Main Authors: Franklin S. Azebaze Agueguia, Paul Talla, Marie C. Okomo Assoumou, Graeme B. Jacobs, Cedric H. Mbakam, Elise Guiedem, Martha Tongo Mesembe, Emilia Lyonga, George Mondinde Ikomey
Format: Article
Language:English
Published: AOSIS 2021-03-01
Series:African Journal of Laboratory Medicine
Subjects:
hbv
cd95-cd95l
cd4+ t-cells
cd8+ t-cells
cirrhosis
Online Access:https://ajlmonline.org/index.php/ajlm/article/view/1224

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