Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals
Vitamin D serum level increase is associated with a reduction in clinical relapse rate, gadolinium-enhancing lesions, new or enlarging T2 lesions and new active lesions in the MRI in MS patients. However, current RCTs assessing the vitamin D supplementation therapeutic effect in MS provide inconclus...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/24/7278 |
| _version_ | 1797457094729793536 |
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| author | Weronika Galus Anna Walawska-Hrycek Michalina Rzepka Ewa Krzystanek |
| author_facet | Weronika Galus Anna Walawska-Hrycek Michalina Rzepka Ewa Krzystanek |
| author_sort | Weronika Galus |
| collection | DOAJ |
| description | Vitamin D serum level increase is associated with a reduction in clinical relapse rate, gadolinium-enhancing lesions, new or enlarging T2 lesions and new active lesions in the MRI in MS patients. However, current RCTs assessing the vitamin D supplementation therapeutic effect in MS provide inconclusive results. Experts recommend vitamin D measurements and implementations among patients with MS. This article discusses an observational study, performed without any intervention to evaluate the vitamin D status and practices among MS patients and professionals in the clinical setting. A total of 139 patients with MS treated by disease-modifying therapy were recruited and fulfilled the standardized questionnaire assessing the vitamin D supplementation practices and vitamin D level influencing factors such as education, insolation, smoking, obesity and current treatment. The collected data were then compared to the patients’ vitamin D serum levels available in medical records at the baseline and after 12 months of observation. Professionals’ practices and recommendations were also assessed. A total of 74.1% patients confirmed vitamin D supplementation, and all patients were administered cholecalciferol, taken orally. However, only 43.69% of the patients achieved an optimal vitamin D concentration (30–50 ng/mL). The lack of a doctor’s recommendation was the most frequent reason for the absence of vitamin D supplementation. The most often recommended vitamin D daily dose was 4000 IU. There was no adverse effect of supplementation observed. Vitamin D status in patients with MS is currently better than in the general population, but still, a significant percentage of patients do not implement vitamin D. |
| first_indexed | 2024-03-09T16:17:14Z |
| format | Article |
| id | doaj.art-e034afcce4e645279e1f8dbe4f288568 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T16:17:14Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e034afcce4e645279e1f8dbe4f2885682023-11-24T15:42:47ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-011124727810.3390/jcm11247278Vitamin D Supplementation Practices among Multiple Sclerosis Patients and ProfessionalsWeronika Galus0Anna Walawska-Hrycek1Michalina Rzepka2Ewa Krzystanek3Department of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Neurology, Faculty of Health Sciences in Katowice, Medical University of Silesia, 40-635 Katowice, PolandVitamin D serum level increase is associated with a reduction in clinical relapse rate, gadolinium-enhancing lesions, new or enlarging T2 lesions and new active lesions in the MRI in MS patients. However, current RCTs assessing the vitamin D supplementation therapeutic effect in MS provide inconclusive results. Experts recommend vitamin D measurements and implementations among patients with MS. This article discusses an observational study, performed without any intervention to evaluate the vitamin D status and practices among MS patients and professionals in the clinical setting. A total of 139 patients with MS treated by disease-modifying therapy were recruited and fulfilled the standardized questionnaire assessing the vitamin D supplementation practices and vitamin D level influencing factors such as education, insolation, smoking, obesity and current treatment. The collected data were then compared to the patients’ vitamin D serum levels available in medical records at the baseline and after 12 months of observation. Professionals’ practices and recommendations were also assessed. A total of 74.1% patients confirmed vitamin D supplementation, and all patients were administered cholecalciferol, taken orally. However, only 43.69% of the patients achieved an optimal vitamin D concentration (30–50 ng/mL). The lack of a doctor’s recommendation was the most frequent reason for the absence of vitamin D supplementation. The most often recommended vitamin D daily dose was 4000 IU. There was no adverse effect of supplementation observed. Vitamin D status in patients with MS is currently better than in the general population, but still, a significant percentage of patients do not implement vitamin D.https://www.mdpi.com/2077-0383/11/24/7278multiple sclerosisvitamin Dsupplementation |
| spellingShingle | Weronika Galus Anna Walawska-Hrycek Michalina Rzepka Ewa Krzystanek Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals Journal of Clinical Medicine multiple sclerosis vitamin D supplementation |
| title | Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals |
| title_full | Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals |
| title_fullStr | Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals |
| title_full_unstemmed | Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals |
| title_short | Vitamin D Supplementation Practices among Multiple Sclerosis Patients and Professionals |
| title_sort | vitamin d supplementation practices among multiple sclerosis patients and professionals |
| topic | multiple sclerosis vitamin D supplementation |
| url | https://www.mdpi.com/2077-0383/11/24/7278 |
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