The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress
Intestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maintain energetic homeostasis in Drosophila melanogast...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28268-x |
| _version_ | 1818887664417374208 |
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| author | Olga Kubrak Takashi Koyama Nadja Ahrentløv Line Jensen Alina Malita Muhammad T. Naseem Mette Lassen Stanislav Nagy Michael J. Texada Kenneth V. Halberg Kim Rewitz |
| author_facet | Olga Kubrak Takashi Koyama Nadja Ahrentløv Line Jensen Alina Malita Muhammad T. Naseem Mette Lassen Stanislav Nagy Michael J. Texada Kenneth V. Halberg Kim Rewitz |
| author_sort | Olga Kubrak |
| collection | DOAJ |
| description | Intestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maintain energetic homeostasis in Drosophila melanogaster. |
| first_indexed | 2024-12-19T16:40:49Z |
| format | Article |
| id | doaj.art-e034d13ae63b4246ba92550680fc92f3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T16:40:49Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e034d13ae63b4246ba92550680fc92f32022-12-21T20:13:48ZengNature PortfolioNature Communications2041-17232022-02-0113111710.1038/s41467-022-28268-xThe gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stressOlga Kubrak0Takashi Koyama1Nadja Ahrentløv2Line Jensen3Alina Malita4Muhammad T. Naseem5Mette Lassen6Stanislav Nagy7Michael J. Texada8Kenneth V. Halberg9Kim Rewitz10Department of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenDepartment of Biology, University of CopenhagenIntestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maintain energetic homeostasis in Drosophila melanogaster.https://doi.org/10.1038/s41467-022-28268-x |
| spellingShingle | Olga Kubrak Takashi Koyama Nadja Ahrentløv Line Jensen Alina Malita Muhammad T. Naseem Mette Lassen Stanislav Nagy Michael J. Texada Kenneth V. Halberg Kim Rewitz The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress Nature Communications |
| title | The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| title_full | The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| title_fullStr | The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| title_full_unstemmed | The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| title_short | The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| title_sort | gut hormone allatostatin c somatostatin regulates food intake and metabolic homeostasis under nutrient stress |
| url | https://doi.org/10.1038/s41467-022-28268-x |
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