1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade
The α-arylation of amides via aryl migration has attracted considerable interest in recent years. Here, the authors report a method for the preparation of bulky α-quaternary amides via a polar-radical crossover enolate oxidation-aryl migration cascade.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30817-3 |
| _version_ | 1811257958702514176 |
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| author | Niklas Radhoff Armido Studer |
| author_facet | Niklas Radhoff Armido Studer |
| author_sort | Niklas Radhoff |
| collection | DOAJ |
| description | The α-arylation of amides via aryl migration has attracted considerable interest in recent years. Here, the authors report a method for the preparation of bulky α-quaternary amides via a polar-radical crossover enolate oxidation-aryl migration cascade. |
| first_indexed | 2024-04-12T18:05:42Z |
| format | Article |
| id | doaj.art-e035ca43aa4f40e3b70e6d5d56e48109 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T18:05:42Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e035ca43aa4f40e3b70e6d5d56e481092022-12-22T03:22:00ZengNature PortfolioNature Communications2041-17232022-06-0113111010.1038/s41467-022-30817-31,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascadeNiklas Radhoff0Armido Studer1Organisch-Chemisches Institut, Westfälische Wilhelms-UniversitätOrganisch-Chemisches Institut, Westfälische Wilhelms-UniversitätThe α-arylation of amides via aryl migration has attracted considerable interest in recent years. Here, the authors report a method for the preparation of bulky α-quaternary amides via a polar-radical crossover enolate oxidation-aryl migration cascade.https://doi.org/10.1038/s41467-022-30817-3 |
| spellingShingle | Niklas Radhoff Armido Studer 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade Nature Communications |
| title | 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade |
| title_full | 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade |
| title_fullStr | 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade |
| title_full_unstemmed | 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade |
| title_short | 1,4-Aryl migration in ketene-derived enolates by a polar-radical-crossover cascade |
| title_sort | 1 4 aryl migration in ketene derived enolates by a polar radical crossover cascade |
| url | https://doi.org/10.1038/s41467-022-30817-3 |
| work_keys_str_mv | AT niklasradhoff 14arylmigrationinketenederivedenolatesbyapolarradicalcrossovercascade AT armidostuder 14arylmigrationinketenederivedenolatesbyapolarradicalcrossovercascade |