Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review

It has been more than 30 years since the first ordered mesoporous silica molecular sieve (MCM-41) was reported, but the enthusiasm for exploiting mesoporous silica is still growing due to its superior properties, such as its controllable morphology, excellent hosting capability, easy functionalizati...

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Main Authors: Qiuping Li, You Zhou
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/5/2013
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author Qiuping Li
You Zhou
author_facet Qiuping Li
You Zhou
author_sort Qiuping Li
collection DOAJ
description It has been more than 30 years since the first ordered mesoporous silica molecular sieve (MCM-41) was reported, but the enthusiasm for exploiting mesoporous silica is still growing due to its superior properties, such as its controllable morphology, excellent hosting capability, easy functionalization, and good biocompatibility. In this narrative review, the brief history of the discovery of mesoporous silica and several important mesoporous silica families are summarized. The development of mesoporous silica microspheres with nanoscale dimensions, hollow mesoporous silica microspheres, and dendritic mesoporous silica nanospheres is also described. Meanwhile, common synthesis methods for traditional mesoporous silica, mesoporous silica microspheres, and hollow mesoporous silica microspheres are discussed. Then, we introduce the biological applications of mesoporous silica in fields such as drug delivery, bioimaging, and biosensing. We hope this review will help people to understand the history of the development of mesoporous silica molecular sieves and become familiar with their synthesis methods and applications in biology.
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spelling doaj.art-e038d65c91864f8aa42559f69ec15ac42023-11-17T08:10:48ZengMDPI AGMolecules1420-30492023-02-01285201310.3390/molecules28052013Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative ReviewQiuping Li0You Zhou1School of Pharmacy, Fuzhou Medical College of Nanchang University, Fuzhou 344000, ChinaState Key Laboratory Base of Novel Functional Materials and Preparation Science, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, ChinaIt has been more than 30 years since the first ordered mesoporous silica molecular sieve (MCM-41) was reported, but the enthusiasm for exploiting mesoporous silica is still growing due to its superior properties, such as its controllable morphology, excellent hosting capability, easy functionalization, and good biocompatibility. In this narrative review, the brief history of the discovery of mesoporous silica and several important mesoporous silica families are summarized. The development of mesoporous silica microspheres with nanoscale dimensions, hollow mesoporous silica microspheres, and dendritic mesoporous silica nanospheres is also described. Meanwhile, common synthesis methods for traditional mesoporous silica, mesoporous silica microspheres, and hollow mesoporous silica microspheres are discussed. Then, we introduce the biological applications of mesoporous silica in fields such as drug delivery, bioimaging, and biosensing. We hope this review will help people to understand the history of the development of mesoporous silica molecular sieves and become familiar with their synthesis methods and applications in biology.https://www.mdpi.com/1420-3049/28/5/2013mesoporous silicamolecular sievesynthesis methoddevelopment historybiological application
spellingShingle Qiuping Li
You Zhou
Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
Molecules
mesoporous silica
molecular sieve
synthesis method
development history
biological application
title Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
title_full Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
title_fullStr Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
title_full_unstemmed Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
title_short Brief History, Preparation Method, and Biological Application of Mesoporous Silica Molecular Sieves: A Narrative Review
title_sort brief history preparation method and biological application of mesoporous silica molecular sieves a narrative review
topic mesoporous silica
molecular sieve
synthesis method
development history
biological application
url https://www.mdpi.com/1420-3049/28/5/2013
work_keys_str_mv AT qiupingli briefhistorypreparationmethodandbiologicalapplicationofmesoporoussilicamolecularsievesanarrativereview
AT youzhou briefhistorypreparationmethodandbiologicalapplicationofmesoporoussilicamolecularsievesanarrativereview