LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting
<p>Abstract</p> <p>Background</p> <p>Conditional gene knockout (cKO) mediated by the Cre/LoxP system is indispensable for exploring gene functions in mice. However, a major limitation of this method is that gene KO is not reversible. A number of methods have been develo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-11-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/10/96 |