Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation
Aim. Comparison of different treatment tactics – medicated antiarrhythmic therapy (AAT) and radiofrequency ablation (RFA) of elderly and senile pa- tients with relapsing atrial fibrillation (AF) as more severe patients with a burdened comorbid background.Material and methods. The study included ...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2018-11-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/1751 |
| _version_ | 1826949675491524608 |
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| author | M. H. Fedorova V. L. Doshchitsin A. V. Chapurnykh |
| author_facet | M. H. Fedorova V. L. Doshchitsin A. V. Chapurnykh |
| author_sort | M. H. Fedorova |
| collection | DOAJ |
| description | Aim. Comparison of different treatment tactics – medicated antiarrhythmic therapy (AAT) and radiofrequency ablation (RFA) of elderly and senile pa- tients with relapsing atrial fibrillation (AF) as more severe patients with a burdened comorbid background.Material and methods. The study included 108 patients with paroxysmal and persistent AF who were in hospital and then under outpatient observation for 2 years. Depending on the method of treatment, patients were divided into 2 groups: the group receiving medicated AAT (n=45) and the group treated with RFA (63 patients). Most patients of the 2nd group (n=60) after the RFA received AAT, i.e. so-called hybrid therapy. These groups were comparable in age (mean age 64.9 and 64.7 years, respectively), sex and underlying pathology, comorbid diseases.Results. In patients who received "hybrid" therapy after 2 years of observation, it was more often possible to preserve the sinus rhythm and achieve a reduction in arrhythmia episodes in comparison with the drug group (95.2% and 86.6%, respectively). Quality of life and the frequency of complications of AAT in these groups of patients were comparable.Conclusion: In elderly and senile patients with paroxysmal and persistent atrial fibrillation, RFA and hybrid therapy was more effective for maintaining sinus rhythm compared to drug therapy. After RFA in this category of patients, in most cases, medicated AAT was used. When choosing the tactics of rational AAT in elderly patients, preference should be given to tactics in which it is possible to achieve an improvement in the quality of life. |
| first_indexed | 2024-03-08T14:02:34Z |
| format | Article |
| id | doaj.art-e03e98188af74a6c9d9de8f69c2dfc0e |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2025-02-17T22:18:19Z |
| publishDate | 2018-11-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-e03e98188af74a6c9d9de8f69c2dfc0e2024-12-04T11:48:15ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532018-11-0114567067710.20996/1819-6446-2018-14-5-670-6771521Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial FibrillationM. H. Fedorova0V. L. Doshchitsin1A. V. Chapurnykh2Central State Medical Academy of Administrative Department of the President of the Russian FederationCentral State Medical Academy of Administrative Department of the President of the Russian FederationCentral Clinical Hospital and Polyclinic of Administrative Department of the President of the Russian FederationAim. Comparison of different treatment tactics – medicated antiarrhythmic therapy (AAT) and radiofrequency ablation (RFA) of elderly and senile pa- tients with relapsing atrial fibrillation (AF) as more severe patients with a burdened comorbid background.Material and methods. The study included 108 patients with paroxysmal and persistent AF who were in hospital and then under outpatient observation for 2 years. Depending on the method of treatment, patients were divided into 2 groups: the group receiving medicated AAT (n=45) and the group treated with RFA (63 patients). Most patients of the 2nd group (n=60) after the RFA received AAT, i.e. so-called hybrid therapy. These groups were comparable in age (mean age 64.9 and 64.7 years, respectively), sex and underlying pathology, comorbid diseases.Results. In patients who received "hybrid" therapy after 2 years of observation, it was more often possible to preserve the sinus rhythm and achieve a reduction in arrhythmia episodes in comparison with the drug group (95.2% and 86.6%, respectively). Quality of life and the frequency of complications of AAT in these groups of patients were comparable.Conclusion: In elderly and senile patients with paroxysmal and persistent atrial fibrillation, RFA and hybrid therapy was more effective for maintaining sinus rhythm compared to drug therapy. After RFA in this category of patients, in most cases, medicated AAT was used. When choosing the tactics of rational AAT in elderly patients, preference should be given to tactics in which it is possible to achieve an improvement in the quality of life.https://www.rpcardio.online/jour/article/view/1751atrial fibrillationcomorbidityantiarrhythmic therapyradiofrequency ablationelderly age |
| spellingShingle | M. H. Fedorova V. L. Doshchitsin A. V. Chapurnykh Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation Рациональная фармакотерапия в кардиологии atrial fibrillation comorbidity antiarrhythmic therapy radiofrequency ablation elderly age |
| title | Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation |
| title_full | Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation |
| title_fullStr | Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation |
| title_full_unstemmed | Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation |
| title_short | Tactics of Antiarrhythmic Therapy in Comorbid Elderly and Senile Patients with Paroxysmal and Recurrent Atrial Fibrillation |
| title_sort | tactics of antiarrhythmic therapy in comorbid elderly and senile patients with paroxysmal and recurrent atrial fibrillation |
| topic | atrial fibrillation comorbidity antiarrhythmic therapy radiofrequency ablation elderly age |
| url | https://www.rpcardio.online/jour/article/view/1751 |
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