The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues
Background: Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The management of peri-implant disease has several protocols, among which is the chemical method HYBENX<sup>®</sup>. The aim of t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/10/5/512 |
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| author | Michele Antonio Lopez Pier Carmine Passarelli Emmanuele Godino Nicolò Lombardo Francesca Romana Altamura Alessandro Speranza Andrea Lopez Piero Papi Giorgio Pompa Antonio D’Addona |
| author_facet | Michele Antonio Lopez Pier Carmine Passarelli Emmanuele Godino Nicolò Lombardo Francesca Romana Altamura Alessandro Speranza Andrea Lopez Piero Papi Giorgio Pompa Antonio D’Addona |
| author_sort | Michele Antonio Lopez |
| collection | DOAJ |
| description | Background: Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The management of peri-implant disease has several protocols, among which is the chemical method HYBENX<sup>®</sup>. The aim of this study is to demonstrate the efficacy of HYBENX<sup>®</sup> in the treatment of peri-implantitis and to compare HYBENX<sup>®</sup> with other chemical agents used in the surgical treatment of peri-implantitis. Methods: The present study included a population of ten subjects with severe peri-implantitis. The procedure used in the study involves the application of HYBENX<sup>®</sup> after open-flap debridement. Each patient has been followed for 12 months after a single application of the decontaminant agent. Clinical and radiographical parameters were recorded at baseline, 3 months, and 12 months after treatment completion. Results: At baseline, a mean pocket probing depth (PPD) of 7.3 ± 0.5 mm and a mean clinical attachment level (CAL) of 8.8 ± 0.8 mm was recorded. An average residual PPD of 4.2 ± 0.5 mm and a mean CAL of 5.2 ± 0.8 mm were observed after 1 year. Additionally, the average of bone gain was about 3.4 mm, with a mean marginal bone level (MBL) change from 5.8 mm (baseline) to 2.4 mm (12 months). In total, 90% of the treated implants reached the success rate after the 1-year follow-up. Only in one case out of ten treated implants was resolution of the disease not achieved. Conclusion: Clinical improvements highlight that the procedure of open-flap debridement (OFD) + HYBENX<sup>®</sup> may be considered an effective technique in the treatment of peri-implantitis. From the results obtained, it can be concluded that the use of HYBENX<sup>®</sup> in the surgical treatment of peri-implantitis is promising. Overall, this protocol demands further studies to better understand the role and potential benefits of HYBENX<sup>®</sup> in the treatment of peri-implantitis. |
| first_indexed | 2024-03-10T11:47:39Z |
| format | Article |
| id | doaj.art-e03ff39a0a614f5c9a8e664c0923406b |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T11:47:39Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-e03ff39a0a614f5c9a8e664c0923406b2023-11-21T17:57:35ZengMDPI AGAntibiotics2079-63822021-04-0110551210.3390/antibiotics10050512The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral TissuesMichele Antonio Lopez0Pier Carmine Passarelli1Emmanuele Godino2Nicolò Lombardo3Francesca Romana Altamura4Alessandro Speranza5Andrea Lopez6Piero Papi7Giorgio Pompa8Antonio D’Addona9Unit of Otolaryngology, University Campus Bio-Medico, 00128 Rome, ItalyDivision of Oral Surgery and Implantology, Institute of Clinical Dentistry, Department of Head and Neck, Catholic University of the Sacred Heart, Gemelli University Polyclinic Foundation, 00168 Rome, ItalyDivision of Oral Surgery and Implantology, Institute of Clinical Dentistry, Department of Head and Neck, Catholic University of the Sacred Heart, Gemelli University Polyclinic Foundation, 00168 Rome, ItalyDivision of Oral Surgery and Implantology, Institute of Clinical Dentistry, Department of Head and Neck, Catholic University of the Sacred Heart, Gemelli University Polyclinic Foundation, 00168 Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, “Sapienza” University of Rome, 00161 Rome, ItalyDivision of Oral Surgery and Implantology, Institute of Clinical Dentistry, Department of Head and Neck, Catholic University of the Sacred Heart, Gemelli University Polyclinic Foundation, 00168 Rome, ItalyUniversidad Europea de Madrid, 28670 Madrid, SpainDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, “Sapienza” University of Rome, 00161 Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, Policlinico Umberto I, “Sapienza” University of Rome, 00161 Rome, ItalyDivision of Oral Surgery and Implantology, Institute of Clinical Dentistry, Department of Head and Neck, Catholic University of the Sacred Heart, Gemelli University Polyclinic Foundation, 00168 Rome, ItalyBackground: Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The management of peri-implant disease has several protocols, among which is the chemical method HYBENX<sup>®</sup>. The aim of this study is to demonstrate the efficacy of HYBENX<sup>®</sup> in the treatment of peri-implantitis and to compare HYBENX<sup>®</sup> with other chemical agents used in the surgical treatment of peri-implantitis. Methods: The present study included a population of ten subjects with severe peri-implantitis. The procedure used in the study involves the application of HYBENX<sup>®</sup> after open-flap debridement. Each patient has been followed for 12 months after a single application of the decontaminant agent. Clinical and radiographical parameters were recorded at baseline, 3 months, and 12 months after treatment completion. Results: At baseline, a mean pocket probing depth (PPD) of 7.3 ± 0.5 mm and a mean clinical attachment level (CAL) of 8.8 ± 0.8 mm was recorded. An average residual PPD of 4.2 ± 0.5 mm and a mean CAL of 5.2 ± 0.8 mm were observed after 1 year. Additionally, the average of bone gain was about 3.4 mm, with a mean marginal bone level (MBL) change from 5.8 mm (baseline) to 2.4 mm (12 months). In total, 90% of the treated implants reached the success rate after the 1-year follow-up. Only in one case out of ten treated implants was resolution of the disease not achieved. Conclusion: Clinical improvements highlight that the procedure of open-flap debridement (OFD) + HYBENX<sup>®</sup> may be considered an effective technique in the treatment of peri-implantitis. From the results obtained, it can be concluded that the use of HYBENX<sup>®</sup> in the surgical treatment of peri-implantitis is promising. Overall, this protocol demands further studies to better understand the role and potential benefits of HYBENX<sup>®</sup> in the treatment of peri-implantitis.https://www.mdpi.com/2079-6382/10/5/512implant dentistryperi-implantitismucositisHYBENXdecontaminationoral surgery |
| spellingShingle | Michele Antonio Lopez Pier Carmine Passarelli Emmanuele Godino Nicolò Lombardo Francesca Romana Altamura Alessandro Speranza Andrea Lopez Piero Papi Giorgio Pompa Antonio D’Addona The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues Antibiotics implant dentistry peri-implantitis mucositis HYBENX decontamination oral surgery |
| title | The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues |
| title_full | The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues |
| title_fullStr | The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues |
| title_full_unstemmed | The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues |
| title_short | The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX<sup>®</sup> as a Decontaminant for Implant Surface and Oral Tissues |
| title_sort | treatment of peri implant diseases a new approach using hybenx sup r sup as a decontaminant for implant surface and oral tissues |
| topic | implant dentistry peri-implantitis mucositis HYBENX decontamination oral surgery |
| url | https://www.mdpi.com/2079-6382/10/5/512 |
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