Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications

<p>Abstract</p> <p>Soft tissue sarcomas of childhood are a group of heterogeneous tumors thought to be derived from mesenchymal stem cells. Surgical resection is effective only in about 50% of cases and resistance to conventional chemotherapy is often responsible for treatment fail...

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Bibliographic Details
Main Authors: Giordano Antonio, Miele Lucio, Ciarapica Roberta, Locatelli Franco, Rota Rossella
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Medicine
Subjects:
EZH2
soft tissue sarcomas
epigenetics
methylation
methyltransferases
Online Access:http://www.biomedcentral.com/1741-7015/9/63

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