Group 3 innate lymphoid cells secret neutrophil chemoattractants and are insensitive to glucocorticoid via aberrant GR phosphorylation

Group 3 innate lymphoid cells secret neutrophil chemoattractants and are insensitive to glucocorticoid via aberrant GR phosphorylation

Abstract Background Patients with neutrophil-mediated asthma have poor response to glucocorticoids. The roles and mechanisms of group 3 innate lymphoid cells (ILC3s) in inducing neutrophilic airway inflammation and glucocorticoid resistance in asthma have not been fully clarified. Methods ILC3s in p...

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Bibliographic Details
Main Authors: Li Xiu He, Ling Yang, Ting Liu, Yi Na Li, Ting Xuan Huang, Lan Lan Zhang, Jian Luo, Chun Tao Liu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Respiratory Research
Subjects:
Asthma
Neutrophil chemoattractant
Glucocorticoid resistant
Group 3 innate lymphoid cells
Neutrophilic inflammation
Online Access:https://doi.org/10.1186/s12931-023-02395-5

Internet

https://doi.org/10.1186/s12931-023-02395-5

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