Depressive symptoms in acromegaly: factors that affect their incidence and severity?
Aim. The study aimed to evaluate the influence of acromegaly on the prevalence and the severity of depressive symptoms in patients with active and inactive disease. Material and Methods. The study group comprised 56 patients with acromegaly, which were divided into two groups based on growth hormon...
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| Format: | Article |
| Language: | English |
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Poznan University of Medical Sciences
2020-09-01
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| Series: | Journal of Medical Science |
| Subjects: | |
| Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/453 |
| _version_ | 1798029064285454336 |
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| author | Adam Malicki Joanna Malicka Emilia Potembska Agnieszka Zwolak Dariusz Malicki Patrycja Rogowska |
| author_facet | Adam Malicki Joanna Malicka Emilia Potembska Agnieszka Zwolak Dariusz Malicki Patrycja Rogowska |
| author_sort | Adam Malicki |
| collection | DOAJ |
| description | Aim. The study aimed to evaluate the influence of acromegaly on the prevalence and the severity of depressive symptoms in patients with active and inactive disease.
Material and Methods. The study group comprised 56 patients with acromegaly, which were divided into two groups based on growth hormone (GH) and insulin-like growth factor (IGF-1) levels, with controlled/cured and with uncontrolled acromegaly. The presence and severity of depressive symptoms were assessed using the Beck Depression Inventory-II (BDI-II).
Results. The mean score of BDI-II in the whole group of patients was 13.43±10.41, with no significant difference in the severity of depressive symptoms between patients with cured/controlled and uncontrolled acromegaly (p=0.620). Similarly, the lack of statistically significant differences was confirmed in patients with micro- and macroadenomas, as well as with and without hypopituitarism. There were no significant correlations between BDI-II scores and GH or IGF-1 levels, patient age or duration of the illness.
Conclusions. Depressive symptoms are common in acromegalic patients even if remission has been attained. They are most likely caused by psychological, non-organic causes. Patients diagnosed with acromegaly should undergo a screening BDI test as a part of comprehensive care, and in the event of elevated levels should be provided with a psychiatric consultation and psychological care. |
| first_indexed | 2024-04-11T19:19:21Z |
| format | Article |
| id | doaj.art-e0446a66259a45f78591cb86c0a1ddea |
| institution | Directory Open Access Journal |
| issn | 2353-9798 2353-9801 |
| language | English |
| last_indexed | 2024-04-11T19:19:21Z |
| publishDate | 2020-09-01 |
| publisher | Poznan University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Science |
| spelling | doaj.art-e0446a66259a45f78591cb86c0a1ddea2022-12-22T04:07:21ZengPoznan University of Medical SciencesJournal of Medical Science2353-97982353-98012020-09-0189310.20883/medical.e453Depressive symptoms in acromegaly: factors that affect their incidence and severity?Adam Malicki0Joanna Malicka1Emilia Potembska2Agnieszka Zwolak3Dariusz Malicki4Patrycja Rogowska5Student of Medical University of Lublin, PolandDepartment of Endocrinology, Medical University of Lublin, PolandDepartment of Psychiatric Nursing, Medical University of Lublin, PolandChair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of Lublin, PolandAlcohol Dependence Treatment Ward, Neuropsychiatric Hospital of Lublin, PolandStudent of Medical University of Lublin, PolandAim. The study aimed to evaluate the influence of acromegaly on the prevalence and the severity of depressive symptoms in patients with active and inactive disease. Material and Methods. The study group comprised 56 patients with acromegaly, which were divided into two groups based on growth hormone (GH) and insulin-like growth factor (IGF-1) levels, with controlled/cured and with uncontrolled acromegaly. The presence and severity of depressive symptoms were assessed using the Beck Depression Inventory-II (BDI-II). Results. The mean score of BDI-II in the whole group of patients was 13.43±10.41, with no significant difference in the severity of depressive symptoms between patients with cured/controlled and uncontrolled acromegaly (p=0.620). Similarly, the lack of statistically significant differences was confirmed in patients with micro- and macroadenomas, as well as with and without hypopituitarism. There were no significant correlations between BDI-II scores and GH or IGF-1 levels, patient age or duration of the illness. Conclusions. Depressive symptoms are common in acromegalic patients even if remission has been attained. They are most likely caused by psychological, non-organic causes. Patients diagnosed with acromegaly should undergo a screening BDI test as a part of comprehensive care, and in the event of elevated levels should be provided with a psychiatric consultation and psychological care.https://jms.ump.edu.pl/index.php/JMS/article/view/453depressionacromegalyBDI-IIBeck Depression Inventory-II |
| spellingShingle | Adam Malicki Joanna Malicka Emilia Potembska Agnieszka Zwolak Dariusz Malicki Patrycja Rogowska Depressive symptoms in acromegaly: factors that affect their incidence and severity? Journal of Medical Science depression acromegaly BDI-II Beck Depression Inventory-II |
| title | Depressive symptoms in acromegaly: factors that affect their incidence and severity? |
| title_full | Depressive symptoms in acromegaly: factors that affect their incidence and severity? |
| title_fullStr | Depressive symptoms in acromegaly: factors that affect their incidence and severity? |
| title_full_unstemmed | Depressive symptoms in acromegaly: factors that affect their incidence and severity? |
| title_short | Depressive symptoms in acromegaly: factors that affect their incidence and severity? |
| title_sort | depressive symptoms in acromegaly factors that affect their incidence and severity |
| topic | depression acromegaly BDI-II Beck Depression Inventory-II |
| url | https://jms.ump.edu.pl/index.php/JMS/article/view/453 |
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