ABT-263 exerts a protective effect on upper urinary tract damage by alleviating neurogenic bladder fibrosis

ABT-263 exerts a protective effect on upper urinary tract damage by alleviating neurogenic bladder fibrosis

AbstractThis study investigated the mechanism of action of ABT-263 in the treatment of neurogenic bladder fibrosis (NBF)and its protective effects against upper urinary tract damage (UUTD). Sixty 12-week-old Sprague-Dawley (SD) rats were randomly divided into sham, sham + ABT-263 (50 mg/kg), NBF, NB...

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Bibliographic Details
Main Authors: Yibo Wen, Junwei Wu, Qingsong Pu, Xiangfei He, Junkui Wang, Jinjin Feng, Yanping Zhang, Feng Si, Jian Guo Wen, Jinghua Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
ABT-263
neurogenic bladder
fibrosis
apoptosis
kidney
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2194440

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