Inibição seletiva da ciclo-oxigenase-2: riscos e benefícios Selective inhibition of cyclooxygenase-2: risks and benefits

Inibição seletiva da ciclo-oxigenase-2: riscos e benefícios Selective inhibition of cyclooxygenase-2: risks and benefits

Os anti-inflamatórios inibidores das ciclo-oxigenases (COX) representam a classe de fármacos mais comumente utilizada. A COX corresponde a uma classe de enzimas conservadas evolutivamente e tem duas isoformas principais: a COX-1 e a COX-2. Seus subprodutos têm papel fundamental na inflamação e na pe...

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Bibliographic Details
Main Authors:	Reila Tainá Mendes, Cassiano Pereira Stanczyk, Regina Sordi, Michel Fleith Otuki, Fábio André dos Santos, Daniel Fernandes
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Reumatologia 2012-10-01
Series:	Revista Brasileira de Reumatologia
Subjects:	inibidores de ciclo-oxigenase 2 doenças cardiovasculares farmacologia cyclooxygenase 2 inhibitors cardiovascular diseases pharmacology
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042012000500011

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