| Summary: | A systematic phytochemical study on the components in the seeds of <i>Allium tuberosum</i> was performed, leading to the isolation of 27 steroidal glycosides (SGs <b>1</b>–<b>27</b>). The structures of SGs were identified mainly by nuclear magnetic resonance and mass spectrometries as well as the necessary chemical evidence. In the SGs, <b>1</b>–<b>10</b> and <b>22</b>–<b>26</b> are new steroidal saponin analogues. An in vitro bioassay indicates that <b>1</b>, <b>2</b>, <b>7</b>, <b>8</b>, <b>10</b>, <b>13</b>–<b>15</b>, <b>20</b>, <b>23</b>, and <b>26</b> display promotional roles in testosterone production of rat Leydig cells with the EC<sub>50</sub> values of 1.0 to 4.5 μM, respectively.
|
|---|