Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment
Summary– Eosinophilic myocarditis (EM) is a rare form of myocarditis that usually presents with heart failure due to eosinophilic infiltration. EM is often a component of hypereosinophilic syndrome (HES). HES is a rare disorder characterized by persistent, marked eosinophilia combined with organ sys...
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| Language: | English |
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KARE Publishing
2016-09-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-09056 |
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| author | Aziz İnan Çelik Ali Deniz Mustafa Tangalay Muhammet Buğra Karaaslan Emine Bağır Kılıç |
| author_facet | Aziz İnan Çelik Ali Deniz Mustafa Tangalay Muhammet Buğra Karaaslan Emine Bağır Kılıç |
| author_sort | Aziz İnan Çelik |
| collection | DOAJ |
| description | Summary– Eosinophilic myocarditis (EM) is a rare form of myocarditis that usually presents with heart failure due to eosinophilic infiltration. EM is often a component of hypereosinophilic syndrome (HES). HES is a rare disorder characterized by persistent, marked eosinophilia combined with organ system dysfunction. A 38-year-old man was admitted to emergency services with left inguinal pain and fever, and was hospitalized with diagnosis of nephrolithiasis and urinary tract infection. Intravenous antibiotic therapy of 3 grams meropenem per day and analgesic of 50 mg pethidine per day were administered. Typical angina pectoris and dyspnea developed approximately 24 hours after treatment. Rash on the chest, and diminished bilateral lung sounds and rales were observed. Nonspecific changes were present on electrocardiogram. Laboratory analysis showed progressively increasing levels of cardiac biomarkers and eosinophilia. Peripheral blood smear, bone marrow aspiration, and biopsy demonstrated eosinophilia. Chest x-ray revealed diffuse, bilateral interstitial and reticulonodular infiltrates. Transthoracic echocardiography showed thickened left ventricle. Coronary angiography revealed normal coronary arteries. EM was suspected, endomyocardial biopsy was performed, and pathologic specimen confirmed the diagnosis. Corticosteroid treatment was initiated, and within 1 day, angina pectoris and dyspnea had dramatically reduced, and cardiac biomarkers and eosinophil count had decreased. Normal chest x-ray was observed after 72 hours. The patient was discharged with steroid treatment. |
| first_indexed | 2024-04-10T13:59:23Z |
| format | Article |
| id | doaj.art-e050424fc73c46cb97eb56eb64106a2f |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:59:23Z |
| publishDate | 2016-09-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-e050424fc73c46cb97eb56eb64106a2f2023-02-15T16:10:19ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692016-09-0144651151310.5543/tkda.2015.09056TKDA-09056Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatmentAziz İnan Çelik0Ali Deniz1Mustafa Tangalay2Muhammet Buğra Karaaslan3Emine Bağır Kılıç4Department Of Cardiology, Cukurova University Faculty Of Medicine, Adana, TurkeyDepartment Of Cardiology, Cukurova University Faculty Of Medicine, Adana, TurkeyDepartment Of Cardiology, Cukurova University Faculty Of Medicine, Adana, TurkeyDepartment Of Cardiology, Cukurova University Faculty Of Medicine, Adana, TurkeyDepartmet Of Pathology, Cukurova University Faculty Of Medicine, Adana, TurkeySummary– Eosinophilic myocarditis (EM) is a rare form of myocarditis that usually presents with heart failure due to eosinophilic infiltration. EM is often a component of hypereosinophilic syndrome (HES). HES is a rare disorder characterized by persistent, marked eosinophilia combined with organ system dysfunction. A 38-year-old man was admitted to emergency services with left inguinal pain and fever, and was hospitalized with diagnosis of nephrolithiasis and urinary tract infection. Intravenous antibiotic therapy of 3 grams meropenem per day and analgesic of 50 mg pethidine per day were administered. Typical angina pectoris and dyspnea developed approximately 24 hours after treatment. Rash on the chest, and diminished bilateral lung sounds and rales were observed. Nonspecific changes were present on electrocardiogram. Laboratory analysis showed progressively increasing levels of cardiac biomarkers and eosinophilia. Peripheral blood smear, bone marrow aspiration, and biopsy demonstrated eosinophilia. Chest x-ray revealed diffuse, bilateral interstitial and reticulonodular infiltrates. Transthoracic echocardiography showed thickened left ventricle. Coronary angiography revealed normal coronary arteries. EM was suspected, endomyocardial biopsy was performed, and pathologic specimen confirmed the diagnosis. Corticosteroid treatment was initiated, and within 1 day, angina pectoris and dyspnea had dramatically reduced, and cardiac biomarkers and eosinophil count had decreased. Normal chest x-ray was observed after 72 hours. The patient was discharged with steroid treatment.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-09056eosinophiliaeosinophilic myocarditiseosinophilic pneumonia. |
| spellingShingle | Aziz İnan Çelik Ali Deniz Mustafa Tangalay Muhammet Buğra Karaaslan Emine Bağır Kılıç Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment Türk Kardiyoloji Derneği Arşivi eosinophilia eosinophilic myocarditis eosinophilic pneumonia. |
| title | Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| title_full | Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| title_fullStr | Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| title_full_unstemmed | Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| title_short | Eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| title_sort | eosinophilic myocarditis associa ted with eosinophilic pneumonia and eosinophilia following antibiotic and narcotic analgesic treatment |
| topic | eosinophilia eosinophilic myocarditis eosinophilic pneumonia. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-09056 |
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