Pulmonary comorbidities associated with chronic obstructive pulmonary disease

<p>Introduction <br />Chronic obstructive pulmonary disease (COPD) is characterized by a relatively irreversible airflow limitation caused by chronic inflammation, in most cases tobacco-related. The impact of COPD on morbidity and mortality at the single-patient level depends upon the s...

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Main Authors: Fabrizio Luppi, Bianca Beghè, Pietro Roversi
Format: Article
Language:English
Published: PAGEPress Publications 2012-12-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/31
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author Fabrizio Luppi
Bianca Beghè
Pietro Roversi
author_facet Fabrizio Luppi
Bianca Beghè
Pietro Roversi
author_sort Fabrizio Luppi
collection DOAJ
description <p>Introduction <br />Chronic obstructive pulmonary disease (COPD) is characterized by a relatively irreversible airflow limitation caused by chronic inflammation, in most cases tobacco-related. The impact of COPD on morbidity and mortality at the single-patient level depends upon the severity of COPD symptoms and the existence of other types of systemic and/or pulmonary disease, also known as co-morbid conditions.</p><p>Materials and methods <br />This review examines the pulmonary diseases commonly associated with COPD, in terms of their prevalence, clinical features, pathogenic mechanisms, prognoses, and implications for management of COPD.</p><p>Results <br />The incidence and prevalence of various pulmonary diseases are significantly increased in patients with COPD. These conditions include symptomatic bronchiectasis, combined pulmonary fibrosis and emphysema, lung cancer, sleep-related respiratory disorders, and pulmonary embolism. Some of these concomitant respiratory diseases have an independent negative impact on the prognosis of COPD patients, and their presence has important implications for treatment of these patients.</p><p>Conclusions <br />Physicians treating patients with COPD need to be aware of these coexisting pulmonary diseases. All patients with COPD should be carefully evaluated to identify pulmonary comorbidities, since they not only influence the prognosis but also have an impact on disease management. The treatment of COPD is no longer restricted exclusively to inhaled therapy. The therapeutic approach to this disease is becoming increasingly multidimensional in view of the fact that successful management of comorbidities might positively affect the course of COPD itself.</p>
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spelling doaj.art-e052c6e8f6794bc1961f3431b7e10ae52023-12-02T21:08:25ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522012-12-016410.4081/itjm.2012.26528Pulmonary comorbidities associated with chronic obstructive pulmonary diseaseFabrizio LuppiBianca BeghèPietro Roversi<p>Introduction <br />Chronic obstructive pulmonary disease (COPD) is characterized by a relatively irreversible airflow limitation caused by chronic inflammation, in most cases tobacco-related. The impact of COPD on morbidity and mortality at the single-patient level depends upon the severity of COPD symptoms and the existence of other types of systemic and/or pulmonary disease, also known as co-morbid conditions.</p><p>Materials and methods <br />This review examines the pulmonary diseases commonly associated with COPD, in terms of their prevalence, clinical features, pathogenic mechanisms, prognoses, and implications for management of COPD.</p><p>Results <br />The incidence and prevalence of various pulmonary diseases are significantly increased in patients with COPD. These conditions include symptomatic bronchiectasis, combined pulmonary fibrosis and emphysema, lung cancer, sleep-related respiratory disorders, and pulmonary embolism. Some of these concomitant respiratory diseases have an independent negative impact on the prognosis of COPD patients, and their presence has important implications for treatment of these patients.</p><p>Conclusions <br />Physicians treating patients with COPD need to be aware of these coexisting pulmonary diseases. All patients with COPD should be carefully evaluated to identify pulmonary comorbidities, since they not only influence the prognosis but also have an impact on disease management. The treatment of COPD is no longer restricted exclusively to inhaled therapy. The therapeutic approach to this disease is becoming increasingly multidimensional in view of the fact that successful management of comorbidities might positively affect the course of COPD itself.</p>http://www.italjmed.org/index.php/ijm/article/view/31BronchiectasisCombined pulmonary fibrosis and emphysemaLung cancerSleep-related respiratory disordersPulmonary embolism
spellingShingle Fabrizio Luppi
Bianca Beghè
Pietro Roversi
Pulmonary comorbidities associated with chronic obstructive pulmonary disease
Italian Journal of Medicine
Bronchiectasis
Combined pulmonary fibrosis and emphysema
Lung cancer
Sleep-related respiratory disorders
Pulmonary embolism
title Pulmonary comorbidities associated with chronic obstructive pulmonary disease
title_full Pulmonary comorbidities associated with chronic obstructive pulmonary disease
title_fullStr Pulmonary comorbidities associated with chronic obstructive pulmonary disease
title_full_unstemmed Pulmonary comorbidities associated with chronic obstructive pulmonary disease
title_short Pulmonary comorbidities associated with chronic obstructive pulmonary disease
title_sort pulmonary comorbidities associated with chronic obstructive pulmonary disease
topic Bronchiectasis
Combined pulmonary fibrosis and emphysema
Lung cancer
Sleep-related respiratory disorders
Pulmonary embolism
url http://www.italjmed.org/index.php/ijm/article/view/31
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