The influence of SARS‐CoV‐2 infection on expression of drug‐metabolizing enzymes and transporters in a hACE2 murine model

The influence of SARS‐CoV‐2 infection on expression of drug‐metabolizing enzymes and transporters in a hACE2 murine model

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the resulting Coronavirus disease 2019 emerged in late 2019 and is responsible for significant morbidity and mortality worldwide. A hallmark of severe COVID‐19 is exaggerated systemic inflammation, regarded as a “cyt...

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Bibliographic Details
Main Authors: Kiran Deshpande, Keith R. Lange, William B. Stone, Christine Yohn, Naomi Schlesinger, Leonid Kagan, Albert J. Auguste, Bonnie L. Firestein, Luigi Brunetti
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Pharmacology Research & Perspectives
Subjects:
COVID‐19
drug transporters
drug‐metabolizing enzymes
hACE2
SARS‐CoV‐2
Online Access:https://doi.org/10.1002/prp2.1071

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