Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial
Introduction Available treatments for hot flashes in patients with breast cancer are not always tolerable or effective for all patients. Methods Patients diagnosed to have primary breast cancer were randomly allocated to receive 10 mg of escitalopram, placebo, or progressive muscle relaxation therap...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-10-01
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| Series: | Journal of Psychosomatic Obstetrics and Gynecology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/0167482X.2021.1985452 |
| _version_ | 1797685803292295168 |
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| author | Maryam Shirzadi Negin Farshchian Arash Nazarpour Soudabeh Eskandari Fahimeh Kahrari Hamed Abdollahpour Ranjbar Somayeh Nazari Issa Hekmati Sara Farhang |
| author_facet | Maryam Shirzadi Negin Farshchian Arash Nazarpour Soudabeh Eskandari Fahimeh Kahrari Hamed Abdollahpour Ranjbar Somayeh Nazari Issa Hekmati Sara Farhang |
| author_sort | Maryam Shirzadi |
| collection | DOAJ |
| description | Introduction Available treatments for hot flashes in patients with breast cancer are not always tolerable or effective for all patients. Methods Patients diagnosed to have primary breast cancer were randomly allocated to receive 10 mg of escitalopram, placebo, or progressive muscle relaxation therapy. Patients were asked to report the frequency and duration of hot flashes during day and night, at baseline and after ten weeks of treatment, and completed the menopause rating scale. Results Eighty-two patients were randomly assigned to receive escitalopram (n = 26), PMRT (n = 28), and placebo (n = 28). PMRT and escitalopram could effectively decrease number and duration of diurnal and nocturnal HFs in patients with breast cancer, with a better effect observed from escitalopram. They could both decrease the total score of MRS. Conclusion Both escitalopram ad PMRT can reveal nocturnal and diurnal HFs in terms of frequency and duration in patients with breast cancer. |
| first_indexed | 2024-03-12T00:56:38Z |
| format | Article |
| id | doaj.art-e056f3363f8545a88d6e8241730c78b3 |
| institution | Directory Open Access Journal |
| issn | 0167-482X 1743-8942 |
| language | English |
| last_indexed | 2024-03-12T00:56:38Z |
| publishDate | 2022-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Psychosomatic Obstetrics and Gynecology |
| spelling | doaj.art-e056f3363f8545a88d6e8241730c78b32023-09-14T12:44:02ZengTaylor & Francis GroupJournal of Psychosomatic Obstetrics and Gynecology0167-482X1743-89422022-10-0143439339910.1080/0167482X.2021.19854521985452Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trialMaryam Shirzadi0Negin Farshchian1Arash Nazarpour2Soudabeh Eskandari3Fahimeh Kahrari4Hamed Abdollahpour Ranjbar5Somayeh Nazari6Issa Hekmati7Sara Farhang8Sleep Disorders Research Center, Kermanshah University of Medical SciencesDepartment of Radiation Oncology, Kermanshah University of Medical SciencesDepartment of Pharmacy, Kermanshah University of Medical SciencesSleep Disorders Research Center, Kermanshah University of Medical SciencesFaculty of Medicine, Kermanshah University of Medical SciencesKoc University College of Social Sciences and HumanitiesSleep Disorders Research Center, Kermanshah University of Medical SciencesUniversity of MaraghehResearch Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical SciencesIntroduction Available treatments for hot flashes in patients with breast cancer are not always tolerable or effective for all patients. Methods Patients diagnosed to have primary breast cancer were randomly allocated to receive 10 mg of escitalopram, placebo, or progressive muscle relaxation therapy. Patients were asked to report the frequency and duration of hot flashes during day and night, at baseline and after ten weeks of treatment, and completed the menopause rating scale. Results Eighty-two patients were randomly assigned to receive escitalopram (n = 26), PMRT (n = 28), and placebo (n = 28). PMRT and escitalopram could effectively decrease number and duration of diurnal and nocturnal HFs in patients with breast cancer, with a better effect observed from escitalopram. They could both decrease the total score of MRS. Conclusion Both escitalopram ad PMRT can reveal nocturnal and diurnal HFs in terms of frequency and duration in patients with breast cancer.http://dx.doi.org/10.1080/0167482X.2021.1985452breast cancerhot flashesescitalopramprogressive muscle relaxation |
| spellingShingle | Maryam Shirzadi Negin Farshchian Arash Nazarpour Soudabeh Eskandari Fahimeh Kahrari Hamed Abdollahpour Ranjbar Somayeh Nazari Issa Hekmati Sara Farhang Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial Journal of Psychosomatic Obstetrics and Gynecology breast cancer hot flashes escitalopram progressive muscle relaxation |
| title | Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial |
| title_full | Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial |
| title_fullStr | Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial |
| title_full_unstemmed | Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial |
| title_short | Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial |
| title_sort | escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer a randomized controlled trial |
| topic | breast cancer hot flashes escitalopram progressive muscle relaxation |
| url | http://dx.doi.org/10.1080/0167482X.2021.1985452 |
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