Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography
PurposeThe aim of this study was to investigate changes in the retinal and choroidal thickness between high myopic amblyopia (HMA), low myopia (LM), moderate myopia (MM), high myopia (HM), and normal group (NG) using a spectral-domain optical coherence tomography (SD-OCT).Materials and MethodsA tota...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-03-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.808409/full |
| _version_ | 1830228340182614016 |
|---|---|
| author | Juan Wan Zhengwei Zhang Zhengwei Zhang Yu Tian |
| author_facet | Juan Wan Zhengwei Zhang Zhengwei Zhang Yu Tian |
| author_sort | Juan Wan |
| collection | DOAJ |
| description | PurposeThe aim of this study was to investigate changes in the retinal and choroidal thickness between high myopic amblyopia (HMA), low myopia (LM), moderate myopia (MM), high myopia (HM), and normal group (NG) using a spectral-domain optical coherence tomography (SD-OCT).Materials and MethodsA total of 75 Chinese children (128 eyes; mean age 10.5 years) were recruited. Retinal thickness (RT) and choroidal thickness (CT) were measured at different locations including subfoveal (SF), and at 0.5 mm/1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to the fovea in superior, nasal, inferior, and temporal sectors using enhanced depth imaging (EDI) system of SD-OCT. Axial length (AL), best-corrected visual acuity (BCVA), and refraction errors were also collected.ResultsNo significant differences were found in subfoveal retinal thickness (SFRT). Moreover, a significantly thinner subfoveal choroidal thickness (SFCT) was found in HMA compared to NG, LM, and MM, but not compared to HM. RT at 0.5 mm to fovea, HMA was significantly thinner compared to LM and MM in the three sectors (superior, inferior, and temporal). Nevertheless, no significant differences were found compared to NG and HM. CT at 0.5 mm to fovea, HMA was the significantly thinnest in all four sectors compared to NG, LM, and MM. RT at 1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to fovea, HMA was thinner compared to NG, LM, and MM. CT at 1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to fovea, HMA was thinner compared to NG, LM, and MM. At the superior and inferior sectors, HMA showed to be statistically thinner compared with HM. Moreover, SFCT in the HMA, HM, and NG were negatively correlated with AL.ConclusionsThinner retina and choroidal tissue appear to be related to HMA, and thus can be used as useful parameters for discovering the underlying mechanisms of the disease. |
| first_indexed | 2024-12-18T10:13:30Z |
| format | Article |
| id | doaj.art-e05aad0b0cb24eb19b51e6e7e7a80603 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-18T10:13:30Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-e05aad0b0cb24eb19b51e6e7e7a806032022-12-21T21:11:23ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-03-01910.3389/fmed.2022.808409808409Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence TomographyJuan Wan0Zhengwei Zhang1Zhengwei Zhang2Yu Tian3Department of Ophthalmology, Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou, ChinaDepartment of Ophthalmology, Affiliated Wuxi Clinical College of Nantong University, Wuxi, ChinaDepartment of Ophthalmology, The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, ChinaDepartment of Ophthalmology, Hunan Children's Hospital, Changsha, ChinaPurposeThe aim of this study was to investigate changes in the retinal and choroidal thickness between high myopic amblyopia (HMA), low myopia (LM), moderate myopia (MM), high myopia (HM), and normal group (NG) using a spectral-domain optical coherence tomography (SD-OCT).Materials and MethodsA total of 75 Chinese children (128 eyes; mean age 10.5 years) were recruited. Retinal thickness (RT) and choroidal thickness (CT) were measured at different locations including subfoveal (SF), and at 0.5 mm/1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to the fovea in superior, nasal, inferior, and temporal sectors using enhanced depth imaging (EDI) system of SD-OCT. Axial length (AL), best-corrected visual acuity (BCVA), and refraction errors were also collected.ResultsNo significant differences were found in subfoveal retinal thickness (SFRT). Moreover, a significantly thinner subfoveal choroidal thickness (SFCT) was found in HMA compared to NG, LM, and MM, but not compared to HM. RT at 0.5 mm to fovea, HMA was significantly thinner compared to LM and MM in the three sectors (superior, inferior, and temporal). Nevertheless, no significant differences were found compared to NG and HM. CT at 0.5 mm to fovea, HMA was the significantly thinnest in all four sectors compared to NG, LM, and MM. RT at 1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to fovea, HMA was thinner compared to NG, LM, and MM. CT at 1.0 mm/1.5 mm/2.0 mm/2.5 mm/3.0 mm to fovea, HMA was thinner compared to NG, LM, and MM. At the superior and inferior sectors, HMA showed to be statistically thinner compared with HM. Moreover, SFCT in the HMA, HM, and NG were negatively correlated with AL.ConclusionsThinner retina and choroidal tissue appear to be related to HMA, and thus can be used as useful parameters for discovering the underlying mechanisms of the disease.https://www.frontiersin.org/articles/10.3389/fmed.2022.808409/fullmyopiaamblyopiaretina thicknesschoroid thicknessOCT |
| spellingShingle | Juan Wan Zhengwei Zhang Zhengwei Zhang Yu Tian Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography Frontiers in Medicine myopia amblyopia retina thickness choroid thickness OCT |
| title | Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography |
| title_full | Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography |
| title_fullStr | Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography |
| title_full_unstemmed | Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography |
| title_short | Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography |
| title_sort | examination of macular retina and choroidal thickness in high myopic amblyopia using spectral domain optical coherence tomography |
| topic | myopia amblyopia retina thickness choroid thickness OCT |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.808409/full |
| work_keys_str_mv | AT juanwan examinationofmacularretinaandchoroidalthicknessinhighmyopicamblyopiausingspectraldomainopticalcoherencetomography AT zhengweizhang examinationofmacularretinaandchoroidalthicknessinhighmyopicamblyopiausingspectraldomainopticalcoherencetomography AT zhengweizhang examinationofmacularretinaandchoroidalthicknessinhighmyopicamblyopiausingspectraldomainopticalcoherencetomography AT yutian examinationofmacularretinaandchoroidalthicknessinhighmyopicamblyopiausingspectraldomainopticalcoherencetomography |