Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation

Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation

Abstract Liver metastasis is the major reason for most of colorectal cancer (CRC) related deaths. Accumulating evidence indicates that CRC patients with non-alcoholic fatty liver disease (NAFLD) are at a greater risk of developing liver metastasis. With the growing prevalence of NAFLD, a better unde...

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Bibliographic Details
Main Authors: Chi Zhang, Yue Zhang, Yan Dong, Ruiyang Zi, Yijie Wang, Yanrong Chen, Chengxiang Liu, Junyi Wang, Xuesong Wang, Jianjun Li, Houjie Liang, Juanjuan Ou
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01770-x

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