Association of tet methylcytosine dioxygenase 2 and 5-hydroxymethylcytosine in endometrioid adenocarcinoma and its clinical significance

Abstract Background Aberrant DNA methylation is a vital molecular alteration commonly detected in type I endometrial cancers (EC), and tet methylcytosine dioxygenase 2 (TET2) and 5-hydroxymethylcytosine (5hmC) play significant roles in DNA demethylation. However, little is known about the function a...

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Bibliographic Details
Main Authors: Lei Kuang, Jingbo Zhang, Yanyu Li, Qing Wang, Jianwei Liu, Bei Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Women's Health
Subjects:
Online Access:https://doi.org/10.1186/s12905-024-03021-2