Nonlethal Furfural Exposure Causes Genomic Alterations and Adaptability Evolution in Saccharomyces cerevisiae

Nonlethal Furfural Exposure Causes Genomic Alterations and Adaptability Evolution in Saccharomyces cerevisiae

ABSTRACT Furfural is a major inhibitor found in lignocellulosic hydrolysate, a promising feedstock for the biofermentation industry. In this study, we aimed to investigate the potential impact of this furan-derived chemical on yeast genome integrity and phenotypic evolution by using genetic screenin...

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Bibliographic Details
Main Authors: Lei Qi, Ying-Xuan Zhu, Ye-Ke Wang, Xing-Xing Tang, Ke-Jing Li, Min He, Yang Sui, Pin-Mei Wang, Dao-Qiong Zheng, Ke Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
chromosome stability
furfural
genomic instability
yeasts
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01216-23

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