Up-regulated expression and aberrant DNA methylation of LEP and SH3PXD2A in pre-eclampsia.

Up-regulated expression and aberrant DNA methylation of LEP and SH3PXD2A in pre-eclampsia.

The primary mechanism underlying pre-eclampsia (PE) remains one of the most burning problems in the obstetrics and gynecology. In this study, we performed an expression profiling screen and detected 1312 genes that were differentially expressed (p<0.05 and fold change >1.5) in PE placentas, in...

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Bibliographic Details
Main Authors: Yuqian Xiang, Yan Cheng, Xiaotian Li, Qiaoli Li, Jiawei Xu, Junyu Zhang, Yun Liu, Qinghe Xing, Lei Wang, Lin He, Xinzhi Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609796?pdf=render

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