Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study
Abstract Objective The aim of this study was to assess the diagnostic value of point-of-care bedside ultrasound (PoCUS) as in usual clinical practice in suspected ankle and fifth metatarsal bone fractures, compared to the standard of radiographic imaging. Methods This prospective study included pati...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | Journal of Foot and Ankle Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13047-020-00387-y |
| _version_ | 1797334105933742080 |
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| author | Aniek Crombach Nasim Azizi Heleen Lameijer Mostafa El Moumni Jan C. ter Maaten |
| author_facet | Aniek Crombach Nasim Azizi Heleen Lameijer Mostafa El Moumni Jan C. ter Maaten |
| author_sort | Aniek Crombach |
| collection | DOAJ |
| description | Abstract Objective The aim of this study was to assess the diagnostic value of point-of-care bedside ultrasound (PoCUS) as in usual clinical practice in suspected ankle and fifth metatarsal bone fractures, compared to the standard of radiographic imaging. Methods This prospective study included patients ≥17 years presenting to the Emergency Department with ankle trauma and positive Ottawa Ankle Rules. All patients underwent PoCUS of the ankle by a (resident) emergency physician, the images were assessed by an ultrasound expert. Both were blinded for the medical history and clinical findings of the patients. Radiography of the ankle followed, evaluated by a radiologist blinded from the PoCUS findings. Primary outcome measures were sensitivity and specificity of PoCUS. Results A total of 242 patients were included, with 35 (22%) clinically significant (non-avulsion) fractures observed with radiography. The sensitivity of PoCUS in detecting clinically significant fractures by all sonographers was 80.0% (95% Confidence Interval (CI) 63.0 to 91.6%), specificity 90.3% (95% CI 83.7 to 94.9%), positive predictive value 70.0% (95% CI 57.0 to 80.3%) and the negative predictive value 94.1% (95% CI 89.1 to 96.9%). The sensitivity of PoCUS in detecting clinically significant fractures by the expert was 82.8% (95% CI 66.3 to 93.4%), specificity 99.2% (95% CI 95.5 to 99.9%), positive predictive value 96.7% (95% CI 80.3 to 99.5%) and the negative predictive value 95.3% (95% CI 91.0 to 98.2%). Conclusion PoCUS combined with the OAR has a good diagnostic value in usual clinical practice in the assessment of suspected ankle and fifth metatarsal bone fractures compared to radiographic imaging. More experience with PoCUS will improve the diagnostic value. Trial registration Registered in the local Research Register, study number 201500597 . |
| first_indexed | 2024-03-08T08:15:52Z |
| format | Article |
| id | doaj.art-e06da655e9614b80893aab6abb1e9f77 |
| institution | Directory Open Access Journal |
| issn | 1757-1146 |
| language | English |
| last_indexed | 2024-03-08T08:15:52Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Foot and Ankle Research |
| spelling | doaj.art-e06da655e9614b80893aab6abb1e9f772024-02-02T07:41:59ZengBMCJournal of Foot and Ankle Research1757-11462020-05-011311710.1186/s13047-020-00387-yPoint-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort studyAniek Crombach0Nasim Azizi1Heleen Lameijer2Mostafa El Moumni3Jan C. ter Maaten4Department of Emergency Medicine, University Medical Centre Groningen, University of GroningenDepartment of Emergency Medicine, University Medical Centre Groningen, University of GroningenDepartment of Emergency Medicine, Medical Centre LeeuwardenDepartment of Surgery, University Medical Centre Groningen, University of GroningenDepartment of Internal Medicine, University Medical Centre Groningen, University of GroningenAbstract Objective The aim of this study was to assess the diagnostic value of point-of-care bedside ultrasound (PoCUS) as in usual clinical practice in suspected ankle and fifth metatarsal bone fractures, compared to the standard of radiographic imaging. Methods This prospective study included patients ≥17 years presenting to the Emergency Department with ankle trauma and positive Ottawa Ankle Rules. All patients underwent PoCUS of the ankle by a (resident) emergency physician, the images were assessed by an ultrasound expert. Both were blinded for the medical history and clinical findings of the patients. Radiography of the ankle followed, evaluated by a radiologist blinded from the PoCUS findings. Primary outcome measures were sensitivity and specificity of PoCUS. Results A total of 242 patients were included, with 35 (22%) clinically significant (non-avulsion) fractures observed with radiography. The sensitivity of PoCUS in detecting clinically significant fractures by all sonographers was 80.0% (95% Confidence Interval (CI) 63.0 to 91.6%), specificity 90.3% (95% CI 83.7 to 94.9%), positive predictive value 70.0% (95% CI 57.0 to 80.3%) and the negative predictive value 94.1% (95% CI 89.1 to 96.9%). The sensitivity of PoCUS in detecting clinically significant fractures by the expert was 82.8% (95% CI 66.3 to 93.4%), specificity 99.2% (95% CI 95.5 to 99.9%), positive predictive value 96.7% (95% CI 80.3 to 99.5%) and the negative predictive value 95.3% (95% CI 91.0 to 98.2%). Conclusion PoCUS combined with the OAR has a good diagnostic value in usual clinical practice in the assessment of suspected ankle and fifth metatarsal bone fractures compared to radiographic imaging. More experience with PoCUS will improve the diagnostic value. Trial registration Registered in the local Research Register, study number 201500597 .http://link.springer.com/article/10.1186/s13047-020-00387-yPoint-of-care bedside ultrasoundPoCUSEmergency ultrasoundBedside ultrasoundEmergency departmentAnkle fractures |
| spellingShingle | Aniek Crombach Nasim Azizi Heleen Lameijer Mostafa El Moumni Jan C. ter Maaten Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study Journal of Foot and Ankle Research Point-of-care bedside ultrasound PoCUS Emergency ultrasound Bedside ultrasound Emergency department Ankle fractures |
| title | Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study |
| title_full | Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study |
| title_fullStr | Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study |
| title_full_unstemmed | Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study |
| title_short | Point-of-care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures; a single blinded prospective diagnostic cohort study |
| title_sort | point of care bedside ultrasound examination for the exclusion of clinically significant ankle and fifth metatarsal bone fractures a single blinded prospective diagnostic cohort study |
| topic | Point-of-care bedside ultrasound PoCUS Emergency ultrasound Bedside ultrasound Emergency department Ankle fractures |
| url | http://link.springer.com/article/10.1186/s13047-020-00387-y |
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