Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana
Thallium (Tl) is a non-essential metal mobilized through industrial processes which can lead to it entering the environment and exerting toxic effects. Plants are fundamental components of all ecosystems. Therefore, understanding the impact of Tl on plant growth and development is of great importanc...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S014765132400366X |
| _version_ | 1797215991731585024 |
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| author | Hsin-Fang Chang Shao-Chin Tseng Mau-Tsu Tang Silver Sung-Yun Hsiao Der-Chuen Lee Shan-Li Wang Kuo-Chen Yeh |
| author_facet | Hsin-Fang Chang Shao-Chin Tseng Mau-Tsu Tang Silver Sung-Yun Hsiao Der-Chuen Lee Shan-Li Wang Kuo-Chen Yeh |
| author_sort | Hsin-Fang Chang |
| collection | DOAJ |
| description | Thallium (Tl) is a non-essential metal mobilized through industrial processes which can lead to it entering the environment and exerting toxic effects. Plants are fundamental components of all ecosystems. Therefore, understanding the impact of Tl on plant growth and development is of great importance for assessing the potential environmental risks of Tl. Here, the responses of Arabidopsis thaliana to Tl were elucidated using physiological, genetic, and transcriptome analyses. Thallium can be absorbed by plant roots and translocated to the aerial parts, accumulating at comparable concentrations throughout plant parts. Genetic evidence supported the regulation of Tl uptake and movement by different molecular compartments within plants. Thallium primarily caused growth inhibition, oxidative stress, leaf chlorosis, and the impairment of K homeostasis. The disturbance of redox balance toward oxidative stress was supported by significant differences in the expression of genes involved in oxidative stress and antioxidant defense under Tl exposure. Reduced GSH levels in cad2–1 mutant rendered plants highly sensitive to Tl, suggesting that GSH has a prominent role in alleviating Tl-triggered oxidative responses. Thallium down-regulation of the expression of LCHII-related genes is believed to be responsible for leaf chlorosis. These findings illuminate some of the mechanisms underlying Tl toxicity at the physiological and molecular levels in plants with an eye toward the future environment management of this heavy metal. |
| first_indexed | 2024-04-24T11:38:52Z |
| format | Article |
| id | doaj.art-e06e52150500455aab38bfb97c3d315d |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-24T11:38:52Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-e06e52150500455aab38bfb97c3d315d2024-04-10T04:28:27ZengElsevierEcotoxicology and Environmental Safety0147-65132024-05-01276116290Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thalianaHsin-Fang Chang0Shao-Chin Tseng1Mau-Tsu Tang2Silver Sung-Yun Hsiao3Der-Chuen Lee4Shan-Li Wang5Kuo-Chen Yeh6Agricultural Biotechnology Research Center, Academia Sinica, Taipei 11529, Taiwan, Republic of ChinaExperimental Facility Division, National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan, Republic of ChinaExperimental Facility Division, National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan, Republic of ChinaInstitute of Earth Sciences, Academia Sinica, Taipei 11529, Taiwan, Republic of ChinaInstitute of Earth Sciences, Academia Sinica, Taipei 11529, Taiwan, Republic of China; Institute of Astronomy and Astrophysics, Academia Sinica, Taipei 11529, Taiwan, Republic of ChinaDepartment of Agricultural Chemistry, National Taiwan University, Taipei 10617, Taiwan, Republic of ChinaAgricultural Biotechnology Research Center, Academia Sinica, Taipei 11529, Taiwan, Republic of China; Corresponding author.Thallium (Tl) is a non-essential metal mobilized through industrial processes which can lead to it entering the environment and exerting toxic effects. Plants are fundamental components of all ecosystems. Therefore, understanding the impact of Tl on plant growth and development is of great importance for assessing the potential environmental risks of Tl. Here, the responses of Arabidopsis thaliana to Tl were elucidated using physiological, genetic, and transcriptome analyses. Thallium can be absorbed by plant roots and translocated to the aerial parts, accumulating at comparable concentrations throughout plant parts. Genetic evidence supported the regulation of Tl uptake and movement by different molecular compartments within plants. Thallium primarily caused growth inhibition, oxidative stress, leaf chlorosis, and the impairment of K homeostasis. The disturbance of redox balance toward oxidative stress was supported by significant differences in the expression of genes involved in oxidative stress and antioxidant defense under Tl exposure. Reduced GSH levels in cad2–1 mutant rendered plants highly sensitive to Tl, suggesting that GSH has a prominent role in alleviating Tl-triggered oxidative responses. Thallium down-regulation of the expression of LCHII-related genes is believed to be responsible for leaf chlorosis. These findings illuminate some of the mechanisms underlying Tl toxicity at the physiological and molecular levels in plants with an eye toward the future environment management of this heavy metal.http://www.sciencedirect.com/science/article/pii/S014765132400366XArabidopsis thalianaGlutathionePhotosynthesisPotassium homeostasisThallium |
| spellingShingle | Hsin-Fang Chang Shao-Chin Tseng Mau-Tsu Tang Silver Sung-Yun Hsiao Der-Chuen Lee Shan-Li Wang Kuo-Chen Yeh Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana Ecotoxicology and Environmental Safety Arabidopsis thaliana Glutathione Photosynthesis Potassium homeostasis Thallium |
| title | Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana |
| title_full | Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana |
| title_fullStr | Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana |
| title_full_unstemmed | Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana |
| title_short | Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana |
| title_sort | physiology and molecular basis of thallium toxicity and accumulation in arabidopsis thaliana |
| topic | Arabidopsis thaliana Glutathione Photosynthesis Potassium homeostasis Thallium |
| url | http://www.sciencedirect.com/science/article/pii/S014765132400366X |
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